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HTT/Huntingtin in selective autophagy and Huntington disease: A foe or a friend within?

Yan-Ning Rui1, Zhen Xu, Bindi Patel

  • 1a Center for Metabolic and Degenerative Diseases; The Brown Foundation Institute of Molecular Medicine; The University of Texas Medical School at Houston ; Houston , TX , USA.

Autophagy
|May 19, 2015
PubMed
Abstract

No abstract available in PubMed .

Keywords:
ATG101, autophagy-related 101ATG13, autophagy-related 13HuntingtinHuntington diseaseKO, knockoutMAP1LC3A, microtubule-associated protein 1 light chain 3 alphaMAPT/Tau, microtubule-associated protein tauMTOR, mechanistic target of rapamycin (serine/threonine kinase)MTORC1MTORC1, MTOR complex 1PRKAA/AMPK, protein kinase, AMP-activated, α catalytic subunitRB1CC1, RB1-inducible coiled-coil 1SQSTM1, sequestosome 1SQSTM1/p62ULK1ULK1, unc-51 like autophagy activating kinase 1.aggrephagycargo recognitionlipophagymitophagynonselective autophagyselective autophagy

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