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[Chronic recurrent-progressive polyradiculoneuritis--Characteristics of autonomic dysfunction].
Rinsho Shinkeigaku = Clinical Neurology
|August 1, 1989
Summary
Patients with chronic-recurrent-progressive polyradiculoneuritis (C-R-P-PRN) showed decreased sweat rates and impaired skin temperature recovery compared to healthy individuals. Autonomic dysfunction was more pronounced in the extremities.
Area of Science:
- Neurology
- Autonomic Neuroscience
Context:
- Chronic-recurrent-progressive polyradiculoneuritis (C-R-P-PRN) is a debilitating neurological condition.
- Autonomic nervous system (ANS) dysfunction can significantly impact patient quality of life.
Purpose:
- To investigate and characterize autonomic dysfunctions in patients with C-R-P-PRN.
- To compare autonomic function parameters between C-R-P-PRN patients and healthy controls.
Summary:
- Autonomic function tests, including thermal sweat rate, local sweat response to pilocarpine and nicotine, skin temperature regulation, and pupillary function, were performed on 12 C-R-P-PRN patients and 16 healthy volunteers.
- Patients with C-R-P-PRN exhibited a reduced sweat rate and slower skin temperature recovery compared to controls.
- Abnormalities in sweat response were more frequent in the forearm and lower leg of C-R-P-PRN patients.
Impact:
- This study highlights the prevalence and pattern of autonomic dysfunctions in C-R-P-PRN.
- Findings contribute to a better understanding of the systemic effects of C-R-P-PRN and may inform clinical management strategies.