Related Experiment Video
Updated: Apr 12, 2026

Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty
Published on: October 6, 2016
Ageing with HIV: a multidisciplinary review
A Calcagno1, S Nozza2, C Muss3
1Unit of Infectious Diseases, Department of Medical Sciences, University of Torino, Torino, Italy. andrea.calcagno@unito.it.
Introduction:
After the introduction of highly active antiretroviral treatment, the course of HIV infection turned into a chronic disease and most of HIV-positive patients will soon be over 50 years old.
Material And Methods:
This paper reviews the multiple aspects that physicians have to face while taking care of HIV-positive ageing patients including the definitions of frailty and the prevalence and risk factors of concomitant diseases. From a therapeutic point of view pharmacokinetic changes and antiretroviral-specific toxicities associated with ageing are discussed; finally therapeutic approaches to frailty are reviewed both in HIV-positive and negative patients.
Conclusion And Discussion:
We conclude by suggesting that the combined use of drugs with the least toxicity potential and the promotion of healthy behaviours (including appropriate nutrition and exercise) might be the best practice for ageing HIV-positive subjects.
More Related Videos
Related Concept Videos
Retrovirus Life Cycles
Pharmacodynamics in Geriatric Patients: Effects of Age
Aging
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
Drug Dosing: Geriatric Patients
The Effect of Aging on Tissues
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism

