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Related Concept Videos

Psychosis and Antipsychotic Drugs: Overview01:28

Psychosis and Antipsychotic Drugs: Overview

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The term "psychosis" refers to a spectrum of mental disorders characterized by abnormal thoughts, perceptions, and behaviors. It can manifest as mood disorders, dementia, delirium with psychotic features, substance-induced psychosis with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Among all these disorders, schizophrenia is the most common psychotic disorder, affecting 1% of the worldwide population. Psychotic...
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Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders01:27

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Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within...
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Schizophrenia01:17

Schizophrenia

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Schizophrenia, a term introduced by Swiss psychiatrist Eugen Bleuler in 1911, describes a severe psychological disorder marked by profound disruptions in attention, thought processes, language, emotion, and interpersonal relationships. The core feature of schizophrenia is psychosis — a state characterized by a fundamental detachment from reality. This disconnection manifests through distorted logic, impaired perception, and atypical behavior, severely affecting the lives of those...
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Psychosis: Goals of Pharmacotherapy01:26

Psychosis: Goals of Pharmacotherapy

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Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
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Positive Symptoms Schizophrenia: Hallucinations and Delusions01:26

Positive Symptoms Schizophrenia: Hallucinations and Delusions

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Schizophrenia is a complex psychiatric disorder characterized by a range of symptoms that significantly impact cognition, behavior, and emotional regulation. Among these, the positive symptoms stand out as they involve the addition or exaggeration of normal mental functions, deviating markedly from typical behavior and perception. Hallucinations and delusions are prominent positive symptoms, each profoundly affecting the individual's experience of reality.
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Hallucinations in...
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Personality Disorders: Paranoid and Schizoid01:22

Personality Disorders: Paranoid and Schizoid

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Personality disorders represent enduring cognition, affect, and behavior patterns that significantly deviate from societal norms. These maladaptive traits often lead to difficulties in various domains, including interpersonal relationships, occupational settings, and overall psychological well-being. Paranoid personality disorder and schizoid personality disorder are two distinct conditions marked by odd or eccentric behavior.
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Related Experiment Video

Updated: Apr 12, 2026

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
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Focus on psychosis.

Wolfgang Gaebel1, Jürgen Zielasek1

  • 1Department of Psychiatry and Psychotherapy, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.

Dialogues in Clinical Neuroscience
|May 20, 2015
PubMed
Summary

Psychosis lacks a unified definition but includes core symptoms like delusions and hallucinations. Research deconstructs psychosis into component symptoms to understand its causes and pathophysiology.

Area of Science:

  • Psychiatry and Clinical Psychology
  • Neuroscience

Background:

  • The concept of psychosis has evolved over 170 years within the framework of mental disorder classifications.
  • Currently, a universally accepted definition for psychosis remains elusive, though it is recognized as a clinical construct encompassing multiple symptoms.

Observation:

  • Core clinical features of psychosis include delusions, hallucinations, and thought disorders.
  • The underlying mechanisms of psychotic symptoms appear to involve neuropsychological processes leading to reality distortion.

Findings:

  • A unified definition for psychosis is lacking.
  • Deconstructing psychosis into its constituent symptoms is crucial for advancing research into its causes and pathophysiology.
  • Current research focuses on differentiating psychosis from normality, exploring genetic factors, and understanding symptom etiology.
Keywords:
classification of mental disordershistory of psychosispsychosisschizophrenia

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Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
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Implications:

  • Understanding the deconstructed components of psychosis can lead to more targeted research and potential therapeutic interventions.
  • Further research into the genetic and neurobiological underpinnings of psychotic symptoms is essential.
  • Clarifying the boundaries between psychosis and normality will aid in diagnosis and treatment strategies.