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Updated: Apr 12, 2026

Assessment of Child Anthropometry in a Large Epidemiologic Study
Published on: February 2, 2017
Short Sleep Duration Is Related to Emerging Cardiovascular Risk Factors in Obese Children
María Navarro-Solera1, Joaquín Carrasco-Luna, Gonzalo Pin-Arboledas
1*Department of Pediatrics, Obstetrics, and Gynecology, University of Valencia †Department of Experimental Science, School Catholic University of Valencia ‡Sleep Unit, Hospital Quirón §Department of Preventive Medicine and Public Health, University of Valencia ||Department of Pediatrics, Dr Peset University Hospital, Valencia, Spain.
Insights
Short sleep duration in obese children is linked to increased central obesity and higher risks for cardiovascular issues, including elevated blood pressure and homocysteine levels. This highlights the importance of adequate sleep for pediatric metabolic health.
Area of Science:
- Pediatric Endocrinology
- Cardiovascular Health
- Sleep Medicine
Background:
- Childhood obesity is a growing public health concern.
- Obesity is associated with an increased risk of cardiovascular disease.
- Sleep disturbances are common in children and may impact metabolic health.
Purpose of the Study:
- To investigate the association between sleep duration and cardiovascular risk factors in obese children.
- To identify specific metabolic and clinical markers influenced by sleep duration in this population.
Main Methods:
- Cross-sectional analysis of 90 obese children (ages 7-16).
- Sleep duration assessed using the BEARS questionnaire and National Sleep Foundation criteria.
- Evaluated various biochemical markers, including glucose, lipids, inflammatory markers, and adipokines.
- Statistical analysis using general lineal and logistic regression models.
Main Results:
- Short sleep duration was significantly associated with more severe central obesity.
- Independent predictors of short sleep duration included increased mean arterial pressure, homocysteine, retinol-binding protein 4 (RBP4), and thyroid-stimulating hormone (TSH).
- No significant association was found between sleep duration and inflammatory markers or adipokines.
Conclusions:
- Inadequate sleep duration exacerbates obesity severity in children.
- Short sleep is a significant risk factor for developing cardiovascular issues in obese children.
- Findings underscore the critical role of sufficient sleep in managing pediatric obesity and preventing cardiometabolic complications.
Objective:
The aim of the present study was to evaluate the influence of sleep duration on cardiovascular risk factors in obese children.
Methods:
Cross-sectional analysis of 90 obese children ages 7 to 16 years. Anthropometric and clinical evaluation with specification of dietary and lifestyle habits was carried out during an office visit. Sleep duration was evaluated by the BEARS (B = bedtime issues, E = excessive daytime sleepiness, A = night awakening, R = regularity and duration of sleep, S = snoring) questionnaire on children's sleep characteristics. Sleep time adequacy by age was assessed according to the criteria of the National Sleep Foundation. Biochemical blood variables indicative of metabolic risk (glucose, lipid profile, and insulin) were obtained. Emergent new factors of metabolic risk, including high-sensitive C-reactive protein, γ-glutamyltranspeptidase, homocysteine, retinol-binding protein 4 (RBP4), thyroid-stimulating hormone (TSH), inflammatory markers, and the adipokines leptin, adiponectin, and ghrelin were also evaluated. The relations between the duration of sleep and these variables were analyzed by general lineal model analysis. Significant variables were introduced in logistic regression analysis to determine the odds ratio (OR) and 95% confidence interval (CI) of cardiometabolic factors with respect to sleep.
Results:
Children who slept for short duration were significantly more at risk of severe central obesity. In the regression model, the mean arterial pressure (odds ratio [OR] 1.10, 95% confidence interval [CI] 1.02-1.17, P = 0.008), homocysteine (OR 1.41, 95% CI 1.08-1.84, P = 0.013), RBP4 (OR 1.78, 95% CI 1.15-2.78, P = 0.010), and TSH (OR 2.01, 95% CI 1.21-3.34, P = 0.007) remain as significant independent predictors related to short sleep duration. We did not find any association between sleep duration and inflammatory markers or adipokines.
Conclusions:
Short sleep duration increases the severity of obesity and is related to cardiovascular risk factors in children.
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