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Updated: Apr 12, 2026

Author Spotlight: Advancing Awake Nasotracheal Intubation with Flexible Video Rhino-Laryngoscopes
Published on: August 2, 2024
GlideScope vs. C-MAC for Awake Upright Laryngoscopy.
Andrea Skye Drenguis1, Jestin N Carlson2
1Department of Emergency Medicine, Allegheny Health Network, Erie, Pennsylvania.
GlideScope (GVL) offers better glottic views than C-MAC during awake upright laryngoscopy. This video laryngoscope study found GVL superior for visualization in healthy volunteers.
Area of Science:
- Anesthesiology
- Airway Management
- Medical Devices
Background:
- Awake upright intubation with video laryngoscopy presents an alternative to traditional endotracheal intubation (ETI).
- This technique may overcome limitations associated with conventional ETI methods.
Purpose of the Study:
- To compare the GlideScope (GVL) and C-MAC video laryngoscopes.
- To evaluate laryngoscopic views and time intervals during awake, upright intubation in volunteers.
Main Methods:
- A prospective, randomized, crossover study was conducted on healthy volunteers.
- Participants underwent awake upright laryngoscopy using GVL and C-MAC under local anesthesia.
- Key metrics included time to glottic view, Percentage of Glottic Opening (POGO) score, Cormack-Lehane grade, and attempts needed.
Main Results:
- GlideScope (GVL) demonstrated a shorter median time to first glottic view compared to C-MAC (7s vs. 9s, p=0.005).
- GVL achieved significantly higher POGO scores (61.25 vs. 5, p<0.001) and better Cormack-Lehane views (1.5 vs. 2, p=0.001).
- Time to best glottic view and number of attempts were similar between the two devices.
Conclusions:
- GlideScope provides superior visualization compared to C-MAC during awake upright laryngoscopy.
- These findings suggest GVL may be a preferred device for this specific intubation technique in healthy individuals.
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