[A man with multiple mucosal lesions and pancytopenia]
Hanneke van Erp-van der Steen1, Mariette C A van Kouwen
1Radboudumc, afd. Maag-, Darm-, en Leverziekten, Nijmegen.
Nederlands Tijdschrift Voor Geneeskunde
|May 21, 2015
Summary
Methotrexate intoxication can cause severe symptoms like oral ulcers, skin lesions, dehydration, and pancytopenia. Discontinuation of folic acid while using methotrexate increases this risk.
Area of Science:
- Toxicology
- Dermatology
- Hematology
Background:
- Methotrexate is a common medication for psoriasis.
- Folic acid supplementation is often recommended with methotrexate therapy.
- Discontinuation of folic acid may increase methotrexate toxicity.
