Related Experiment Video
Updated: Apr 12, 2026
Laboratory Scale Production and Purification of a Therapeutic Antibody
Published on: January 24, 2017
Therapeutic antibodies: Discovery, design and deployment
Paul A Ramsland1, Andrew T Hutchinson2, Paul J Carter3
1Centre for Biomedical Research, Burnet Institute, Melbourne, VIC 3004, Australia; Department of Immunology, Monash University, Alfred Medical Research and Education Precinct, Melbourne, VIC 3004, Australia; Department of Surgery Austin Health, University of Melbourne, Heidelberg, VIC 3084, Australia; School of Biomedical Sciences, CHIRI Biosciences, Curtin University, Perth, WA 6845, Australia.
Therapeutic antibodies show great promise for treating cancer and inflammatory diseases. Ongoing research focuses on antibody engineering and cell-based therapies to overcome challenges and advance cures for complex human conditions.
Area of Science:
- Immunology
- Oncology
- Pharmacology
Background:
- Therapeutic antibodies have advanced significantly, showing efficacy in treating cancer, autoimmune disorders, and chronic inflammation.
- Novel antibody formats and genetically engineered cell-based therapies are emerging, leveraging the immune system for disease treatment.
Discussion:
- The field of therapeutic antibodies is rapidly evolving, with ongoing advancements in antibody engineering.
- Harnessing the immune system through cell-based therapies offers new avenues for treating intractable diseases.
Key Insights:
- Significant progress has been made in applying therapeutic antibodies to various human diseases.
- Antibody engineering is crucial for developing next-generation antibody formats and cell-based therapies.
Outlook:
- Despite advancements, challenges remain in the basic and applied research of therapeutic antibodies.
- This special issue explores the discovery, design, and deployment of antibodies as therapeutics, highlighting future directions.
