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Stenting of Native Right Ventricular Outflow Tract Obstructions in Symptomatic Infants
Harald Bertram1, Mathias Emmel2, Peter Ewert3
1Medizinische Hochschule Hannover, Hannover, Germany.
Insights
Right ventricular outflow tract (RVOT) stenting is a safe and effective initial treatment for infants with heart conditions. This procedure improves oxygen saturation and serves as a successful bridge to surgical repair.
Area of Science:
- Pediatric Cardiology
- Interventional Cardiology
- Congenital Heart Disease
Background:
- Symptomatic young infants with congenital heart defects often require initial palliation.
- Right ventricular outflow tract (RVOT) obstruction is a common defect requiring intervention.
- Surgical repair in very young or high-risk infants can be challenging.
Purpose of the Study:
- To evaluate the feasibility, safety, and effectiveness of RVOT stenting in young infants.
- To assess RVOT stenting as a potential bridge to surgical repair.
- To determine outcomes in infants with severe congenital heart defects undergoing RVOT stenting.
Main Methods:
- A multicenter study involving 35 infants undergoing RVOT stenting between 2009 and 2011.
- Patients included those with hypoxemic spells, respiratory support, or severe malformations.
- Data collected on procedural success, complications, reinterventions, and subsequent surgical repair.
Main Results:
- RVOT stenting was technically successful in 33 of 35 patients, improving oxygen saturation from 77% to 90%.
- No procedural complications occurred; 17 patients required 1-3 reinterventions during follow-up.
- 27 patients underwent successful surgical repair after stenting, with no perioperative deaths.
Conclusions:
- RVOT stenting is a safe and effective initial management strategy for symptomatic young infants.
- This approach provides successful palliation and serves as a bridge to surgical repair.
- Stenting is a viable option for infants not suitable for immediate surgical therapy or at high risk.
Objective:
To assess feasibility, safety and effectiveness of right ventricular outflow tract (RVOT) stenting in symptomatic young infants.
Methods:
Multicentre evaluation of 35 patients intended to undergo RVOT stenting in 11 pediatric cardiac centres from 2009 to August 2011.
Results:
Median age and weight at the time of first stent implantation were 8 weeks and 3.3 kg, with 40% of patients <3 kg. A total of 19 patients had suffered from hypoxemic spells, 8 patients were ventilated, 6 on inotropic support and 5 on prostaglandin infusion. Severe concomitant malformations were present in 11 patients, and acute infections in 2. Stenting of the RVOT was successfully performed in 33 patients, improving oxygen saturation from a median of 77 to 90% 2 days after intervention. Besides the 2 patients in whom RVOT stenting was not successful for technical reasons, there were no procedural complications. In 17 of 33 patients, 1-3 reinterventions were performed during follow-up, less than half of those were reinterventions in the RVOT. A total of 27 patients have undergone successful surgical repair 4-162 (median 19.5) weeks after initial RVOT stent implantation, 2 patients are still waiting. There were no perioperative deaths.
Conclusions:
Stenting of the RVOT provides a safe and effective management strategy for initial palliation in symptomatic young infants, including those patients not suitable or at higher risk for surgical therapy.
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