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Published on: September 19, 2018
Site-Specific Relationship Between Intracranial Aneurysm and Aortic Aneurysm
Yong-Won Shin1, Keun-Hwa Jung2, Jangsup Moon1
1From the Department of Neurology, Seoul National University Hospital, Seoul, South Korea (Y.-W.S., K.-H.J., J.M., S.-T.L., S.K.L., K.C.); and Department of Neurology, The Armed Forces Capital Hospital, Sungnam, Gyeunggido, South Korea (J.-K.R.).
Intracranial aneurysms (IAs) and aortic aneurysms (AAs) show location-specific relationships. Anterior circulation IAs are common with ascending AAs, while internal carotid artery IAs are more frequent with infrarenal AAs.
Area of Science:
- Vascular Surgery
- Neurology
- Cardiology
Background:
- Aortic pathology, including bicuspid aortic valve and coarctation of the aorta, is linked to intracranial aneurysms (IAs).
- Previous studies have not fully explored the heterogeneity of IA locations in relation to aortic aneurysm (AA) subtypes.
Purpose of the Study:
- To investigate a potential location-specific relationship between intracranial aneurysms (IAs) and aortic aneurysms (AAs).
Main Methods:
- Retrospective analysis of 71 patients with 97 IAs and concurrent AAs from 2005-2014.
- Categorization of IAs by location (internal carotid artery, anterior circulation, posterior arteries) and AAs by type (ascending, descending, infrarenal, multiple).
Main Results:
- Significant differences in the distribution of anterior circulation-IAs and internal carotid artery-IAs were observed across AA groups (P=0.001 and P=0.01).
- Anterior circulation-IAs were most common with ascending AAs, whereas internal carotid artery-IAs were most frequent with infrarenal AAs.
- Posterior artery IA data was insufficient for analysis.
Conclusions:
- The distinct distribution patterns of IAs in relation to AA location suggest shared, site-specific pathomechanisms.
- This finding highlights the importance of considering aneurysm location when evaluating the relationship between intracranial and aortic aneurysms.
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