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Updated: Apr 12, 2026

Early Pathological and Magnetic Resonance Detection of Cerebral Injury Using a Rat Model of Neonatal Hypoxic Ischemic Encephalopathy
Published on: October 28, 2022
Language in children with neonatal hypoxic-ischemic encephalopathy
Chenia Martinez1, Luciana Carneiro1, Luíza Vernier1
1Departamento de Fonoaudiologia, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS, Brazil.
Neonatal hypoxic-ischemic encephalopathy (NHIE) can impair language development in infants. This study found a significant inverse correlation between age and language skills, indicating developmental delays in affected children.
Area of Science:
- Pediatric Neurology
- Developmental Psychology
- Speech-Language Pathology
Background:
- Neonatal hypoxic-ischemic encephalopathy (NHIE) is a significant cause of neurological injury in newborns.
- NHIE can negatively impact a child's cognitive and language development.
- Understanding language acquisition in children with NHIE is crucial for early intervention.
Purpose of the Study:
- To investigate the impact of NHIE on language acquisition and development in infants and young children.
- To identify potential delays in language skills among children diagnosed with NHIE.
- To correlate developmental milestones with language proficiency in this population.
Main Methods:
- A cohort of seventy children diagnosed with NHIE, aged 1 to 24 months, were assessed.
- The Brunet-Lezine Scale was utilized to evaluate developmental and language skills.
- Statistical analysis was performed using SPSS 13.0 software to determine correlations.
Main Results:
- A significant inverse correlation (r = -0.566, p = 0.028) was observed between age and language performance.
- Language tasks became more complex and dependent on individual action with increasing age.
- Findings suggest delays in language development are associated with NHIE and the assessment scale used.
Conclusions:
- The study confirms that NHIE can lead to impairments in language development.
- Early and focused attention on language skills is essential for children affected by NHIE.
- Professionals should prioritize monitoring language development during the critical early stages of childhood.
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