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Test of immunopotentialization in colposcopy--a clinical evaluation
M Balajewicz1, J Dembowska, R Klimek
1Institute for Obstetrics and Gynecology, Copernicus University School of Medicine, Cracow, Poland.
European Journal of Obstetrics, Gynecology, and Reproductive Biology
|December 1, 1989
Summary
Gynatren-immunopotentialization therapy effectively treated infertile women, normalizing cervical health and reducing cervical intraepithelial neoplasia (CIN) in many cases. The treatment showed significant improvements in cervical milieu and regression of CIN.
Area of Science:
- Gynecology
- Immunology
- Oncology
Background:
- Cervical intraepithelial neoplasia (CIN) is a significant concern in women's reproductive health.
- Infertile women may present with co-existing cervical pathologies, complicating treatment outcomes.
- Immunopotentiation strategies are being explored for gynecological conditions.
Purpose of the Study:
- To evaluate the efficacy of Gynatren-immunopotentialization in treating infertile women.
- To assess the impact of this therapy on cervical milieu and cervical intraepithelial neoplasia (CIN).
- To compare treatment outcomes between women with and without CIN.
Main Methods:
- 52 infertile women (ages 19-35) received Gynatren-immunopotentialization (3 vaccinations over 4 weeks).
- Participants were divided into two groups: those with and without diagnosed CIN.
- Colposcopic examinations were conducted at baseline, week 2, and week 4.
Main Results:
- Four weeks of therapy led to cervical milieu normalization, with infection regression in 68.2% (Group I) and 56% (Group II).
- Cervical intraepithelial neoplasia (CIN) disappeared in 66% of cases, with a 7-fold decrease in CIN II in others.
- Regression of inflammation and cervical pathology normalization were less pronounced in women with CIN.
Conclusions:
- Gynatren-immunopotentialization demonstrates significant potential in improving cervical health in infertile women.
- The therapy effectively reduces cervical infections and cervical intraepithelial neoplasia (CIN).
- While beneficial, the therapeutic impact on CIN regression is more evident in women without pre-existing CIN.