Related Experiment Video
Updated: Apr 12, 2026

Investigating Intestinal Inflammation in DSS-induced Model of IBD
Published on: February 1, 2012
[New opportunities in the diagnosis of ulcerative colitis]
Purpose Of The Study:
to analyze the expression of markers of apoptosis and proliferation in patients with ulcerative colitis.
Materials And Methods:
in 80 patients with ulcerative colitis the analysis of expression of apoptosis marker BAX and proliferation marker Ki-67, as well as the cell cycle regulator p53 in biopsy materials of the mucous membrane of the colon was carried out.
The Results:
decreased cell proliferative activity and increase of the apoptosis rate depending on the severity, the localization of the inflammatory process and its endoscopic activity were registered.
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