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Cationic PTD/CPP-mediated macromolecular delivery: charging into the cell.

Peter Lönn1,2, Steven F Dowdy1

  • 1a 1 UCSD School of Medicine, Department of Cellular and Molecular Medicine , 9500 Gilman Dr., La Jolla, CA 92093-0686, USA sdowdy@ucsd.edu.

Expert Opinion on Drug Delivery
|May 22, 2015
PubMed
Summary

Protein transduction domains (PTDs), also known as cell-penetrating peptides (CPPs), are essential for delivering macromolecular therapeutics into cells. These peptides show great potential for treating diseases, with over 25 clinical trials underway.

Keywords:
CPPPTDdeliverymacromolecular therapeutics

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