Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulse rhythm01:30

Pulse rhythm

1.7K
Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac...
1.7K
Electrocardiogram01:29

Electrocardiogram

8.6K
An electrocardiogram (ECG or EKG) is a critical diagnostic tool that records the electrical signals produced by the heart during each heartbeat. This recording is achieved through electrodes placed strategically on the arms, legs, and chest. The electrocardiograph amplifies these signals and produces 12 distinct tracings, offering a comprehensive understanding of the heart's electrical activity.
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and...
8.6K
Pulse Oximetry01:24

Pulse Oximetry

1.7K
Pulse oximetry, or SpO2, is a non-invasive method for continuously monitoring arterial oxygen saturation (SaO2). This procedure involves attaching a probe or sensor to the patient's fingertip, forehead, earlobe, or nose bridge. The sensor works by detecting changes in oxygen saturation levels through light signals generated by the oximeter and reflected by the pulsing blood under the probe.
Purpose
Average SpO2 values are greater than 95%. If the readings fall below 90%, it indicates that...
1.7K
Equipments Used To Measure Blood Pressure01:30

Equipments Used To Measure Blood Pressure

4.0K
Direct Method
This invasive approach involves cannulating a peripheral artery. During each cardiac contraction, pressure generates mechanical motion within the catheter, transmitted through rigid, fluid-filled tubing to a transducer. This transducer converts mechanical motion into electrical signals displayed as waveforms on a monitor. An automatic flushing system prevents blood backflow. Due to the potential risk of unexpected arterial blood loss, this method is primarily used in intensive...
4.0K
Assessing Blood pressure using a doppler ultrasound01:19

Assessing Blood pressure using a doppler ultrasound

3.0K
To obtain accurate blood pressure measurements in clinical settings, especially when traditional methods are insufficient, healthcare professionals utilize the Doppler ultrasound technique. This method uses high-frequency sound waves to detect blood flow within the arteries, which is crucial for patients with conditions that complicate circulatory system assessment.
Pre-Procedural Guidelines for Doppler Ultrasound Blood Pressure Assessment:
Preparation of Equipment:
3.0K
Electrocardiogram Fundamentals01:28

Electrocardiogram Fundamentals

2.0K
Introduction
An electrocardiogram (ECG) is a diagnostic tool for identifying cardiac conditions such as arrhythmias, conduction abnormalities, and myocardial ischemia.
Definition
An electrocardiogram (ECG) visualizes the heart's electrical activity by tracing the electrical movement associated with each heartbeat on a graph or monitor. As the heart beats, an electrical wave passes through it, correlating with the cardiac cycle events.
Parts of an ECG
An ECG utilizes electrodes on the skin...
2.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Butterworth Filtering at 500 Hz Optimizes PPG-Based Heart Rate Variability Analysis for Wearable Devices: A Comparative Study.

Sensors (Basel, Switzerland)·2025
Same author

New Aging Index Using Signal Features of Both Photoplethysmograms and Acceleration Plethysmograms.

Healthcare informatics research·2017
Same author

Aging Index using Photoplethysmography for a Healthcare Device: Comparison with Brachial-Ankle Pulse Wave Velocity.

Healthcare informatics research·2015
Same author

Nuclear factor of activated T cells mediates fluid shear stress- and tensile strain-induced Cox2 in human and murine bone cells.

Bone·2009
Same author

Nuclear factor of activated T cell mediates proinflammatory gene expression in response to mechanotransduction.

Annals of the New York Academy of Sciences·2007
Same author

Mechanical loading differentially regulates membrane-bound and soluble RANKL availability in MC3T3-E1 cells.

Annals of the New York Academy of Sciences·2006

Related Experiment Video

Updated: Apr 12, 2026

Ultrasound-based Pulse Wave Velocity Evaluation in Mice
08:07

Ultrasound-based Pulse Wave Velocity Evaluation in Mice

Published on: February 14, 2017

14.8K

Wave detection in acceleration plethysmogram.

Jae Mok Ahn1

  • 1Department of Electronics Engineering, College of Information and Electronics Engineering, Hallym University, Chuncheon, Korea.

Healthcare Informatics Research
|May 22, 2015
PubMed
Summary
This summary is machine-generated.

A new algorithm and preamplifier can accurately detect acceleration plethysmogram (APG) wave indices from photoplethysmography (PPG) signals. This technology aids in simple, real-time vascular aging evaluation for early atherosclerosis screening.

Keywords:
Acceleration PlethysmogramArterial StiffnessHealthcarePhotoplethysmographyVascular Aging

More Related Videos

Analyzing Long-Term Electrocardiography Recordings to Detect Arrhythmias in Mice
06:07

Analyzing Long-Term Electrocardiography Recordings to Detect Arrhythmias in Mice

Published on: May 23, 2021

4.6K
Software for Analysis of Heart Rate and Blood Pressure Time-series Data from the Valsalva Maneuver
14:28

Software for Analysis of Heart Rate and Blood Pressure Time-series Data from the Valsalva Maneuver

Published on: June 27, 2025

1.3K

Related Experiment Videos

Last Updated: Apr 12, 2026

Ultrasound-based Pulse Wave Velocity Evaluation in Mice
08:07

Ultrasound-based Pulse Wave Velocity Evaluation in Mice

Published on: February 14, 2017

14.8K
Analyzing Long-Term Electrocardiography Recordings to Detect Arrhythmias in Mice
06:07

Analyzing Long-Term Electrocardiography Recordings to Detect Arrhythmias in Mice

Published on: May 23, 2021

4.6K
Software for Analysis of Heart Rate and Blood Pressure Time-series Data from the Valsalva Maneuver
14:28

Software for Analysis of Heart Rate and Blood Pressure Time-series Data from the Valsalva Maneuver

Published on: June 27, 2025

1.3K

Area of Science:

  • Biomedical Engineering
  • Cardiovascular Physiology
  • Signal Processing

Background:

  • Photoplethysmography (PPG) and its second derivative, acceleration plethysmography (APG), show promise for predicting atherosclerosis risk factors.
  • Extracting APG wave indices (a, b, c, d) from fingertip PPG signals presents significant challenges for early disease detection.

Purpose of the Study:

  • To develop a novel wave detection algorithm and preamplifier for accurate APG signal analysis.
  • To enable real-time extraction of APG wave indices for improved cardiovascular health assessment.

Main Methods:

  • Utilized the 4th order derivative of PPG to enhance APG waveform separation and wave detection success rates.
  • Designed a preamplifier with a Sallen-Key low pass filter and a microcontroller-based wave detection algorithm.
  • Incorporated programmable gain control, mathematical differentials, and a digital IIR notch filter for signal processing.

Main Results:

  • The digital IIR filter's frequency response was evaluated, and a pulse train for wave index identification was generated.
  • Programmable gain control ensured consistent APG amplitude output despite variations in PPG input.
  • The mean value of the a wave index was 1,106.45 ± 47.75 in 164 subjects.

Conclusions:

  • The proposed algorithm and preamplifier effectively extract APG wave indices in real-time.
  • This technology offers a simple and valuable tool for assessing vascular aging.
  • The findings support the use of this system in basic healthcare devices for cardiovascular evaluation.