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    Global polio eradication efforts in 2014-2015 saw progress, with wild poliovirus (WPV) cases decreasing in Nigeria but increasing in Afghanistan and Pakistan. Sustained immunization activities are crucial to stop WPV transmission worldwide.

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    Area of Science:

    • Public Health
    • Epidemiology
    • Global Health Security

    Background:

    • The World Health Organization (WHO) aims for global polio eradication, with wild poliovirus (WPV) transmission now limited to Afghanistan, Nigeria, and Pakistan.
    • While WPV types 2 and 3 have been largely eliminated, WPV type 1 remains a threat, alongside circulating vaccine-derived poliovirus (cVDPV) in under-immunized populations.
    • Polio eradication was declared a programmatic emergency for global public health in 2012 and international WPV spread a public health emergency in 2014.

    Purpose of the Study:

    • To summarize global progress in polio eradication during the 2014-2015 period.
    • To update previous reports on the status of wild poliovirus (WPV) and vaccine-derived poliovirus (cVDPV) transmission.
    • To highlight challenges and necessary actions for achieving global polio eradication.

    Main Methods:

    • The report summarizes global data on polio cases reported in 2014.
    • Analysis of WPV transmission trends in endemic countries (Afghanistan, Nigeria, Pakistan).
    • Review of progress and challenges in implementing supplementary immunization activities (SIAs).

    Main Results:

    • A total of 359 wild poliovirus (WPV) cases were reported globally in 2014 across nine countries.
    • Nigeria experienced a substantial decrease in WPV cases, while Afghanistan and Pakistan saw an increase.
    • Progress has been made towards interrupting WPV transmission, but challenges remain, particularly in Afghanistan and Pakistan.

    Conclusions:

    • Sustained programmatic enhancements are essential to interrupt WPV transmission globally.
    • Improving the quality of supplementary immunization activities (SIAs) is critical in Afghanistan and Pakistan.
    • Preventing the international exportation of WPV to polio-free countries remains a key objective.