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Particle Agglutination Method for Poliovirus Identification
Published on: April 20, 2011
Progress toward polio eradication - worldwide, 2014-2015
Abstract:
In 1988, the World Health Assembly of the World Health Organization (WHO) resolved to eradicate polio worldwide. Wild poliovirus (WPV) transmission has been interrupted in all but three countries (Afghanistan, Nigeria, and Pakistan). No WPV type 2 cases have been detected worldwide since 1999, and the last WPV type 3 case was detected in Nigeria in November 2012; since 2012, only WPV type 1 has been detected. Circulating vaccine-derived poliovirus (cVDPV), usually type 2, continues to cause cases of paralytic polio in communities with low population immunity. In 2012, the World Health Assembly declared global polio eradication "a programmatic emergency for global public health", and in 2014, WHO declared the international spread of WPV to previously polio-free countries to be "a public health emergency of international concern". This report summarizes global progress toward polio eradication during 2014-2015 and updates previous reports. In 2014, a total of 359 WPV cases were reported in nine countries worldwide. Although reported WPV cases increased in Pakistan and Afghanistan, cases in Nigeria decreased substantially in 2014, and encouraging progress toward global WPV transmission interruption has occurred. Overcoming ongoing challenges to interruption of WPV transmission globally will require sustained programmatic enhancements, including improving the quality of supplementary immunization activities (SIAs) to interrupt transmission in Afghanistan and Pakistan and to prevent WPV exportation to polio-free countries.
Insights
Global polio eradication efforts in 2014-2015 saw progress, with wild poliovirus (WPV) cases decreasing in Nigeria but increasing in Afghanistan and Pakistan. Sustained immunization activities are crucial to stop WPV transmission worldwide.
Area of Science:
- Public Health
- Epidemiology
- Global Health Security
Background:
- The World Health Organization (WHO) aims for global polio eradication, with wild poliovirus (WPV) transmission now limited to Afghanistan, Nigeria, and Pakistan.
- While WPV types 2 and 3 have been largely eliminated, WPV type 1 remains a threat, alongside circulating vaccine-derived poliovirus (cVDPV) in under-immunized populations.
- Polio eradication was declared a programmatic emergency for global public health in 2012 and international WPV spread a public health emergency in 2014.
Purpose of the Study:
- To summarize global progress in polio eradication during the 2014-2015 period.
- To update previous reports on the status of wild poliovirus (WPV) and vaccine-derived poliovirus (cVDPV) transmission.
- To highlight challenges and necessary actions for achieving global polio eradication.
Main Methods:
- The report summarizes global data on polio cases reported in 2014.
- Analysis of WPV transmission trends in endemic countries (Afghanistan, Nigeria, Pakistan).
- Review of progress and challenges in implementing supplementary immunization activities (SIAs).
Main Results:
- A total of 359 wild poliovirus (WPV) cases were reported globally in 2014 across nine countries.
- Nigeria experienced a substantial decrease in WPV cases, while Afghanistan and Pakistan saw an increase.
- Progress has been made towards interrupting WPV transmission, but challenges remain, particularly in Afghanistan and Pakistan.
Conclusions:
- Sustained programmatic enhancements are essential to interrupt WPV transmission globally.
- Improving the quality of supplementary immunization activities (SIAs) is critical in Afghanistan and Pakistan.
- Preventing the international exportation of WPV to polio-free countries remains a key objective.
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