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Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

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Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

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MRI Pre- and Post-Embolization Enhancement Patterns Predict Surgical Outcomes in Intracranial Meningiomas.

Rushna Ali¹, Muhib Khan², Victor Chang¹

¹Departments of Neurosurgery Henry Ford Health System, Detroit, MI, 48202.

Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging

|May 22, 2015

Summary

Preoperative embolization improves surgical outcomes for intracranial meningioma. Magnetic resonance imaging (MRI) enhancement patterns, quantified by embolization fraction (EF), predict reduced blood loss and better patient recovery.

Keywords:

Embolization contrast enhancement magnetic resonance imaging meningiomas outcome

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Area of Science:

Neurosurgery
Neuroradiology
Oncology

Background:

Meningiomas are tumors that arise from the meninges, the membranes that surround the brain and spinal cord.
Surgical resection is the primary treatment for intracranial meningiomas, but significant blood loss can complicate the procedure.
Preoperative embolization is a technique used to reduce blood supply to tumors before surgery, potentially improving outcomes.

Purpose of the Study:

To assess the impact of preoperative embolization on surgical outcomes for intracranial meningioma resection.
To determine if magnetic resonance imaging (MRI) enhancement patterns can quantify embolization efficacy.
To correlate embolization efficacy with surgical facilitation and postoperative functional status.

Main Methods:

A prospective database of 89 patients undergoing meningioma resection (2004-2010) was analyzed.
Fifty-two patients received preoperative embolization; embolization fraction (EF) was calculated using pre- and postembolization MRI scans.
Surgical outcomes were evaluated using Karnofsky performance score (KPS) and Glasgow Outcome Score (GOS).

Main Results:

Adequate embolization (58% of patients) was associated with decreased intraoperative blood loss.
Higher embolization fraction (EF) correlated with reduced intraoperative blood loss (r = -.319, P = .022).
Greater embolization extent correlated with better postsurgical outcomes, as measured by KPS (r = .279, P = .044).

Conclusions:

Preoperative embolization is an effective adjunct in managing intracranial meningiomas.
The embolization fraction (EF), derived from MRI enhancement patterns, serves as a reliable measure of embolization efficacy.
Improved embolization efficacy correlates with enhanced surgical facilitation and superior postoperative functional outcomes.