Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Related Rates01:18

Related Rates

205
When two or more physical quantities are linked by a single relationship, a change in one variable necessarily affects the others. This interdependence forms the basis of related rates analysis, which examines how different quantities change with respect to time. A classic physical example is an expanding balloon, where the size of the balloon changes continuously as air is added.For a hot air balloon, the inflated envelope is commonly idealized as a perfect sphere to simplify mathematical...
205
Density00:56

Density

21.1K
Density is an important characteristic of substances, crucial in determining whether an object sinks or floats in a fluid. Its SI unit is kg/m3, and its cgs unit is g/cm3. The density of an object helps in identifying its composition, and also reveals information about the phase of the matter and its substructure. The densities of liquids and solids are roughly comparable, consistent with the fact that their atoms are in close contact. However, gases have much lower densities than liquids and...
21.1K
Pressure Relationships in Thoracic Cavity01:24

Pressure Relationships in Thoracic Cavity

8.6K
Breathing, otherwise known as pulmonary ventilation, is the process of air movement into and out of the lungs. The main mechanisms propelling pulmonary ventilation are atmospheric pressure (Patm), intra-pulmonary (Ppul ) or intra-alveolar pressure (Palv) within the alveoli, and intrapleural pressure (Pip) within the pleural cavity.
Breathing Mechanisms
Both intra-alveolar and intrapleural pressures rely on specific lung properties. The ability to breathe—allowing air to enter the lungs...
8.6K
Breathing01:05

Breathing

66.8K
The process of breathing, inhaling and exhaling, involves the coordinated movement of the chest wall, the lungs, and the muscles that move them. Two muscle groups with important roles in breathing are the diaphragm, located directly below the lungs, and the intercostal muscles, which lie between the ribs. When the diaphragm contracts, it moves downward, increasing the volume of the thoracic cavity and creating more room for the lungs to expand. When the intercostal muscles contract, the ribs...
66.8K
Pulmonary Ventilation: Inhalation01:24

Pulmonary Ventilation: Inhalation

10.4K
Pulmonary ventilation is a vital process that ensures the exchange of oxygen and carbon dioxide in the lungs. It refers to the movement of air into and out of the lungs, enabling the body to obtain oxygen and remove waste carbon dioxide. In this article, we will explore the intricacies of pulmonary ventilation, including its underlying principles, mechanisms, and the interplay of pressures within the respiratory system.
Boyle's law becomes particularly pertinent when examining respiratory...
10.4K
Density, Specific Weight, Specific Gravity and Compressibility of Fluid01:27

Density, Specific Weight, Specific Gravity and Compressibility of Fluid

2.8K
Density, specific weight, specific gravity, and compressibility are fundamental properties of fluids. Density is the mass per unit volume, characterizing the mass of a fluid system. It influences buoyancy, pressure, flow dynamics, viscosity, thermal conductivity, and sound propagation. For instance, in pipeline design, accurate density measurements ensure that the pipeline can handle the fluid's mass.
Specific weight represents the weight per unit volume and is calculated by multiplying...
2.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dental disease among adults with and without HIV in the MACS/WIHS Combined Cohort Study (MWCCS).

BMC oral health·2026
Same author

Menopause Is Associated With Lower Lung Function in Women With and Without HIV.

Chest·2026
Same author

Z variant heterozygosity in alpha-1 antitrypsin deficiency: disease risk and treatment implications.

Orphanet journal of rare diseases·2026
Same author

Understanding Nebulizer Utilization by Patients and Healthcare Providers: A COPD Foundation Nebulizer Consortium Survey Study.

International journal of chronic obstructive pulmonary disease·2026
Same author

Reconsidering Vitamin D Supplementation in Pulmonary Disease: The Case for Targeted Respiratory Delivery.

Chronic obstructive pulmonary diseases (Miami, Fla.)·2026
Same author

Dysbiosis of the nasal microbiome is associated with prospective acute exacerbation of COPD.

Microbiome·2026
Same journal

Independent Prognostic Contributions of Anti-Ro52 and Anti-MDA5 in Autoimmune-Associated Interstitial Lung Disease.

Chest·2026
Same journal

Lung aeration and gas exchange in SGA or AGA infants with moderate-severe BPD: secondary analysis of the PATH-BPD study.

Chest·2026
Same journal

Lung Cancer Incidence and Mortality after Negative Low-Dose CT Screening Results.

Chest·2026
Same journal

Symptom prevalence and impact on lung cancer risk in the SUMMIT study.

Chest·2026
Same journal

How I Do It: De-escalation of Prostacyclin-Based Therapy in Patients Treated With Sotatercept.

Chest·2026
Same journal

Eisenmenger Syndrome: The Pulmonology Perspective.

Chest·2026
See all related articles

Related Experiment Video

Updated: Apr 12, 2026

Author Spotlight: Advances in Quantifying Microvascular Density in Aging Murine Lungs
10:00

Author Spotlight: Advances in Quantifying Microvascular Density in Aging Murine Lungs

Published on: January 3, 2025

4.5K

Lung density changes with growth and inflation.

H Brown Robert1, A Wise Robert2, Gregory Kirk3

  • 1Department of Anesthesiology, Johns Hopkins University, Baltimore, MD; Department of Medicine, Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD; Environmental Health Sciences, Division of Physiology, Johns Hopkins University, Baltimore, MD.

Chest
|May 22, 2015
PubMed
Summary
This summary is machine-generated.

Larger lungs in adults have lower density, indicating existing structures enlarge rather than new alveoli forming. This impacts understanding lung diseases like COPD.

More Related Videos

Measurement of the Pressure-volume Curve in Mouse Lungs
09:49

Measurement of the Pressure-volume Curve in Mouse Lungs

Published on: January 27, 2015

19.6K
Quantification of Cellular Densities and Antigenic Properties using Magnetic Levitation
05:25

Quantification of Cellular Densities and Antigenic Properties using Magnetic Levitation

Published on: May 17, 2021

3.1K

Related Experiment Videos

Last Updated: Apr 12, 2026

Author Spotlight: Advances in Quantifying Microvascular Density in Aging Murine Lungs
10:00

Author Spotlight: Advances in Quantifying Microvascular Density in Aging Murine Lungs

Published on: January 3, 2025

4.5K
Measurement of the Pressure-volume Curve in Mouse Lungs
09:49

Measurement of the Pressure-volume Curve in Mouse Lungs

Published on: January 27, 2015

19.6K
Quantification of Cellular Densities and Antigenic Properties using Magnetic Levitation
05:25

Quantification of Cellular Densities and Antigenic Properties using Magnetic Levitation

Published on: May 17, 2021

3.1K

Area of Science:

  • Pulmonary Medicine
  • Radiology
  • Human Anatomy

Background:

  • Lung growth from childhood can occur by increasing air volume or acinar units.
  • Lung tissue density changes with inflation, but remains constant with new unit formation.
  • Investigated CT scan density in human subjects of varying sizes at different lung volumes.

Purpose of the Study:

  • To determine if lung enlargement involves increased air volume or new acinar units.
  • To correlate lung size with CT scan density in human subjects.

Main Methods:

  • 501 subjects underwent chest CT scans at full inspiration and end expiration.
  • Pulmonary function tests including spirometry and diffusing capacity were performed.
  • CT scan density was measured in relation to lung size.

Main Results:

  • A significant negative correlation (r = -0.72, P = .001) was found between lung size and mean lung density.
  • Larger lungs exhibited significantly lower mean lung density.
  • Density changes across subjects mirrored changes within subjects at different lung volumes.

Conclusions:

  • Lung structure differs between individuals with larger and smaller lungs.
  • Lung growth into adulthood involves enlargement of existing structures, not increased alveoli.
  • Greater air spaces in larger lungs may influence spontaneous pneumothorax and COPD pathogenesis.