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UGT1A1*28 polymorphism influences glucuronidation of bazedoxifene

T Trdan Lušin, A Mrhar, J Trontelj

    Die Pharmazie
    |May 23, 2015
    PubMed
    Summary

    The UGT1A1*28 genetic variation significantly impacts how the body processes bazedoxifene, a drug used for osteoporosis. This polymorphism leads to substantially reduced metabolic clearance, especially in individuals with the *28/*28 genotype.

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