Related Experiment Video
Updated: Apr 12, 2026

13:35
Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
Published on: May 17, 2024
5.0K
Correlation between nipple elevation and breast resection weight: How to preoperatively plan breast reduction.
Mariagrazia Moio1, Fabrizio Schonauer1
1Unit of Plastic, Reconstructive, Aesthetic Surgery, University of Naples "Federico II", Via Pansini 5, 80100 Naples, NA, Italy.
Summary
A simple nipple-areola complex (NAC) lift distance measurement reliably predicts breast reduction weight. This objective measure aids in surgical planning and classifying breast reduction indications for improved patient outcomes.
Area of Science:
- Plastic Surgery
- Surgical Outcomes
- Patient Classification
Background:
- Breast hypertrophy often causes functional limitations and impacts self-esteem.
- Accurate preoperative prediction of resected breast tissue is crucial for surgical planning and healthcare reimbursement.
- Existing preoperative measurements for predicting breast tissue weight show variable correlation with actual outcomes.
Purpose of the Study:
- To introduce and validate a simple, reliable preoperative measurement for predicting breast reduction weight.
- To establish the correlation between nipple-areola complex (NAC) lift distance and the amount of breast tissue removed.
- To develop a practical tool for preoperative planning in breast reduction surgeries.
Main Methods:
- A prospective study evaluated 128 patients undergoing bilateral breast reduction.
- The nipple-areola complex (NAC) lift distance was measured preoperatively.
- Linear regression and Pearson's correlation tested the relationship between NAC lift distance and resected tissue weight.
Main Results:
- A strong positive correlation (r: 0.87; p < 0.001) was found between NAC lift distance and removed breast tissue weight.
- The average resection weight was 686.65 g, with an average NAC lift distance of 7.6 cm.
- A mean of 81 g/cm of tissue was removed for lifts between 6-12 cm, and 70 g/cm for lifts >12 cm.
Conclusions:
- The NAC lift distance is an objective, repeatable, and reliable measure for predicting breast tissue resection weight.
- This simple measurement aids in classifying breast reduction indications and optimizing surgical planning.
- The findings support the use of NAC lift distance for more accurate preoperative assessment in breast reduction surgery.

