Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Positive Symptoms Schizophrenia: Hallucinations and Delusions01:26

Positive Symptoms Schizophrenia: Hallucinations and Delusions

1.0K
Schizophrenia is a complex psychiatric disorder characterized by a range of symptoms that significantly impact cognition, behavior, and emotional regulation. Among these, the positive symptoms stand out as they involve the addition or exaggeration of normal mental functions, deviating markedly from typical behavior and perception. Hallucinations and delusions are prominent positive symptoms, each profoundly affecting the individual's experience of reality.
Hallucinations
Hallucinations in...
1.0K
Psychosis: Goals of Pharmacotherapy01:26

Psychosis: Goals of Pharmacotherapy

676
Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
676
Treatment Strategies for Psychological Disorders01:24

Treatment Strategies for Psychological Disorders

944
Treatment approaches for psychological disorders fall into three main categories: psychological, biological, and sociocultural. Each approach targets different aspects of mental health, requiring varying levels of education and training.
Psychological therapies focus on modifying emotions, thoughts, and behaviors through talking, interpreting, listening, rewarding, challenging, and modeling. Clinical psychologists, counselors, and social workers commonly practice psychotherapy. Clinical...
944
Psychosis and Antipsychotic Drugs: Overview01:28

Psychosis and Antipsychotic Drugs: Overview

1.2K
The term "psychosis" refers to a spectrum of mental disorders characterized by abnormal thoughts, perceptions, and behaviors. It can manifest as mood disorders, dementia, delirium with psychotic features, substance-induced psychosis with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Among all these disorders, schizophrenia is the most common psychotic disorder, affecting 1% of the worldwide population. Psychotic...
1.2K
Personality Disorders: Paranoid and Schizoid01:22

Personality Disorders: Paranoid and Schizoid

1.1K
Personality disorders represent enduring cognition, affect, and behavior patterns that significantly deviate from societal norms. These maladaptive traits often lead to difficulties in various domains, including interpersonal relationships, occupational settings, and overall psychological well-being. Paranoid personality disorder and schizoid personality disorder are two distinct conditions marked by odd or eccentric behavior.
Paranoid Personality Disorder
Paranoid personality disorder is...
1.1K
Positive Symptoms of Schizophrenia: Hallucinations and Delusions01:30

Positive Symptoms of Schizophrenia: Hallucinations and Delusions

1.1K
Schizophrenia is a complex mental health disorder that can manifest with various positive symptoms, including thought, movement, and behavior disorders. These symptoms significantly disrupt cognitive and motor functions, leading to profound effects on an individual's ability to engage with the world.
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes...
1.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Psychiatry and the geriatric syndromes - creating constructive interfaces.

BJPsych bulletin·2017
Same author

Oral health education (advice and training) for people with serious mental illness.

The Cochrane database of systematic reviews·2016
Same author

Treatments for Delusional Disorder.

Schizophrenia bulletin·2015
Same author

Social engagement may be as important as cognitive stimulation therapy in dementia.

BMJ (Clinical research ed.)·2012
Same author

Oral health advice for people with serious mental illness.

The Cochrane database of systematic reviews·2011

Related Experiment Video

Updated: Apr 12, 2026

MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder
08:20

MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder

Published on: August 11, 2015

14.8K

Treatments for delusional disorder.

Mike Skelton1, Waqqas Ahmad Khokhar, Simon P Thacker

  • 1Department of Psychiatry, The University of Nottingham, Institute of Mental Health, Triumph Road, Nottingham, UK, NG7 2TU.

The Cochrane Database of Systematic Reviews
|May 23, 2015
PubMed
Summary

Limited research exists for delusional disorder treatments. Cognitive Behavioural Therapy (CBT) showed some benefit in social self-esteem, but more high-quality trials are needed for effective treatment recommendations.

More Related Videos

Protocol for Repetitive Transcranial Magnetic Stimulation with Symptom Provocation to Treat Obsessive-compulsive Disorder
11:17

Protocol for Repetitive Transcranial Magnetic Stimulation with Symptom Provocation to Treat Obsessive-compulsive Disorder

Published on: November 25, 2025

886
How to Use the H1 Deep Transcranial Magnetic Stimulation Coil for Conditions Other than Depression
07:00

How to Use the H1 Deep Transcranial Magnetic Stimulation Coil for Conditions Other than Depression

Published on: January 23, 2017

25.2K

Related Experiment Videos

Last Updated: Apr 12, 2026

MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder
08:20

MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder

Published on: August 11, 2015

14.8K
Protocol for Repetitive Transcranial Magnetic Stimulation with Symptom Provocation to Treat Obsessive-compulsive Disorder
11:17

Protocol for Repetitive Transcranial Magnetic Stimulation with Symptom Provocation to Treat Obsessive-compulsive Disorder

Published on: November 25, 2025

886
How to Use the H1 Deep Transcranial Magnetic Stimulation Coil for Conditions Other than Depression
07:00

How to Use the H1 Deep Transcranial Magnetic Stimulation Coil for Conditions Other than Depression

Published on: January 23, 2017

25.2K

Area of Science:

  • Psychiatry
  • Clinical Psychology

Background:

  • Delusional disorder is recognized but challenging to treat.
  • Antipsychotic medications are common, with growing interest in psychological therapies like CBT.

Purpose of the Study:

  • To assess the effectiveness of medications and psychotherapy against placebo for delusional disorder.

Main Methods:

  • Searched the Cochrane Schizophrenia Group's Trials Register for relevant randomized controlled trials (RCTs).
  • Extracted data independently and performed fixed-effect meta-analyses for dichotomous and continuous data.
  • Assessed risk of bias and used GRADE for evidence quality.

Main Results:

  • Only one small RCT (n=17) met inclusion criteria, comparing CBT to supportive psychotherapy.
  • Medication trials lacked usable data due to poor reporting.
  • CBT showed a positive effect on social self-esteem (very low quality evidence); dropout rates were lower in the CBT group but not statistically significant (moderate quality evidence).

Conclusions:

  • A significant lack of high-quality RCTs for delusional disorder exists.
  • Insufficient evidence to support evidence-based treatment recommendations.
  • Further high-quality, specifically designed RCTs with robust reporting are crucial.