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Three Laboratory Procedures for Assessing Different Manifestations of Impulsivity in Rats
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Serotonin and impulsive aggression.

Emil F Coccaro1, Jennifer R Fanning1, K Luan Phan2

  • 11Clinical Neuroscience & Psychopharmacology Research Unit,Department of Psychiatry (MC#3077),Pritzker School of Medicine,University of Chicago,Chicago,Illinois,USA.

CNS Spectrums
|May 23, 2015
PubMed
Summary
This summary is machine-generated.

Neurotransmitter function, particularly serotonin, plays a key role in aggression. Further research into the neurobiology of aggression may lead to improved treatments for this destructive behavior.

Keywords:
Aggressionneuroimagingneurotransmittersreceptorsserotonin

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Area of Science:

  • Neuroscience
  • Behavioral Science

Background:

  • Aggression, while having evolutionary roots, is frequently maladaptive in modern society.
  • Decades of research link neurotransmitter function to aggressive behaviors, primarily focusing on the serotonin hypothesis.

Purpose of the Study:

  • To explore the complex neurobiological underpinnings of aggression.
  • To identify potential new therapeutic targets for aggression.

Main Methods:

  • Review of pre-clinical research.
  • Application of advanced neuroimaging techniques.

Main Results:

  • The neurobiology of aggression is more complex than previously understood.
  • Current treatments for aggression show limitations.

Conclusions:

  • Continued research into the neurobiology of aggression is crucial.
  • Novel insights may yield more effective interventions for aggression.