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Malignant melanoma lately diagnosed.

G M Lennon, M Griffin, D S O'Briain

Irish Medical Journal

|September 1, 1989

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Patients in Dublin present with late-stage malignant melanoma, indicating a need for greater public awareness. This study highlights a concerning rise in melanoma incidence and delayed diagnoses, impacting prognosis.

Area of Science:

Dermatology
Oncology
Epidemiology

Background:

Clinical observations suggested patients in Dublin presented with late-stage malignant melanoma.
A retrospective review was conducted to investigate this clinical impression.

Purpose of the Study:

To assess the stage at presentation and prognosis of malignant melanoma patients in Dublin.
To evaluate trends in malignant melanoma incidence and patient awareness over a 10-year period.

Main Methods:

A 10-year retrospective review of 186 malignant melanoma patients' pathological data.
Clinical follow-up was obtained for 151 patients (80%), with a mean follow-up of 35 months.

Main Results:

Malignant melanoma incidence increased by over 100% between 1976-1980 and 1981-1985.

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A significant delay in presentation was observed (mean 21 months), with only 45% of lesions <1.5mm deep.

Females had a higher survival rate (70% at 5 years) compared to males (43%), presenting with better prognosis lesions.

Conclusions:

Results suggest an increase in malignant melanoma incidence and mortality in the studied population.
Patients demonstrate a lack of awareness regarding pigmented lesions, leading to late presentation and deep, poor-prognosis tumors.