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Autosomal recessive congenital ichthyoses in the Czech Republic
H Bučková1, H Nosková2,3, R Borská2
1Pediatric Clinic, University Hospital Brno, Brno, Czech Republic.
The British Journal of Dermatology
|May 23, 2015
Abstract
No abstract available in PubMed .
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Pedigree Analysis
Overview
Sex-linked Disorders
Like autosomes, sex chromosomes contain a variety of genes necessary for normal body function. When a mutation in one of these genes results in biological deficits, the disorder is considered sex-linked.
Incomplete Dominance
Gregor Mendel's work (1822 - 1884) was primarily focused on pea plants. Through his initial experiments, he determined that every gene in a diploid cell has two variants called alleles inherited from each parent. He suggested that amongst these two alleles, one allele is dominant in character and the other recessive. The combination of alleles determines the phenotype of a gene in an organism.

