Related Experiment Video
Updated: Apr 12, 2026
Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography
Published on: March 26, 2020
Effects of Retinal Angiography on Optical Coherence Tomography Measurements
Young-Joon Jo1, Hyung-Bin Lim, Soo-Hyun Lee
1Department of Ophthalmology, Chungnam National University College of Medicine, Daejeon, Republic of Korea.
Purpose:
To evaluate the effects of retinal angiography, using fluorescein and indocyanine green dyes, on optical coherence tomography (OCT) measurements.
Methods:
In total, 76 eyes from 76 consecutive patients were included. Macular cube 512 × 128 combination scanning and optic disc 200 × 200 scanning using spectral-domain (SD)-OCT were performed twice, before and after retinal angiography, with fluorescein or indocyanine green. Signal strength, regional retinal thickness of the 9 Early Treatment Diabetic Retinopathy Study subfields, total macular volume, and retinal nerve fiber layer thickness obtained before and after angiography were compared. Repeatability was also investigated.
Results:
Comparing the results of OCT measured before and after retinal angiography, there was no statistically significant difference in any parameter assessed. The interclass correlation values for each measurement were all >0.808 (range 0.808-0.999).
Conclusion:
Retinal angiography using fluorescein and indocyanine green dyes has no significant effect on OCT measurements.
