Related Experiment Video
Updated: Apr 12, 2026

Detecting the Lyme Disease Spirochete, Borrelia Burgdorferi, in Ticks Using Nested PCR
Published on: February 4, 2018
Lyme disease in children
1Hofstra North Shore-LIJ School of Medicine, Hempstead, NY 11549, USA; Department of Pediatrics, Southside Hospital, 301 East Main Street, Bay Shore, NY 11706, USA; Pediatric Infectious Diseases, Cohen Children's Medical Center, New Hyde Park, NY 11040, USA.
Insights
Lyme disease in children shares adult treatment protocols but requires avoiding doxycycline in those under 8. Early detection of elevated intracranial pressure is crucial to prevent vision loss in pediatric Lyme disease.
Area of Science:
- Pediatrics
- Infectious Diseases
- Public Health
Background:
- Lyme disease is a growing public health concern, particularly in pediatric populations.
- Understanding age-specific nuances in Lyme disease diagnosis and management is critical for effective pediatric care.
- Tick-borne illnesses require vigilant prevention and prompt treatment strategies.
Purpose of the Study:
- To outline the diagnosis and management of Lyme disease in children.
- To highlight key differences in pediatric Lyme disease care compared to adults.
- To provide guidance on serologic testing and prevention of tick bites in children.
Main Methods:
- Review of current clinical guidelines and literature on pediatric Lyme disease.
- Analysis of age-specific treatment recommendations, particularly regarding antibiotic choices.
- Emphasis on recognizing and managing specific pediatric presentations like elevated intracranial pressure.
Main Results:
- Lyme disease diagnosis and management in children largely mirrors adult protocols, with notable exceptions.
- Doxycycline is contraindicated as an initial empiric treatment for children aged 8 years and younger.
- Children may develop insidious elevated intracranial pressure during acute disseminated Lyme disease, necessitating prompt intervention to preserve vision.
- Pediatric patients with Lyme disease, including late disseminated Lyme arthritis, generally have an excellent prognosis.
- Guidance on appropriate use of serologic tests is provided.
Conclusions:
- Pediatric Lyme disease management requires specific considerations, particularly antibiotic selection for younger children.
- Awareness of potential complications like elevated intracranial pressure is vital for preventing long-term sequelae.
- Pediatricians and family practitioners must be proficient in the prevention and management of tick bites and Lyme disease in children.
Abstract:
The diagnosis and management of Lyme disease in children is similar to that in adults with a few clinically relevant exceptions. The use of doxycycline as an initial empiric choice is to be avoided for children 8 years old and younger. Children may present with insidious onset of elevated intracranial pressure during acute disseminated Lyme disease; prompt diagnosis and treatment of this condition is important to prevent loss of vision. Children who acquire Lyme disease have an excellent prognosis even when they present with the late disseminated manifestation of Lyme arthritis. Guidance on the judicious use of serologic tests is provided. Pediatricians and family practitioners should be familiar with the prevention and management of tick bites, which are common in children.
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