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Updated: Apr 12, 2026

Measuring Sperm Guidance and Motility within the Caenorhabditis elegans Hermaphrodite Reproductive Tract
Published on: June 6, 2019
Behavioral mechanisms of mammalian sperm guidance
Serafin Perez-Cerezales, Sergii Boryshpolets, Michael Eisenbach1
1Department of Biological Chemistry, The Weizmann Institute of Science, 7610001 Rehovot, Israel.
Abstract:
In mammals, sperm guidance in the oviduct appears essential for successful sperm arrival at the oocyte. Hitherto, three different potential sperm guidance mechanisms have been recognized: thermotaxis, rheotaxis, and chemotaxis, each of them using specific stimuli - a temperature gradient, fluid flow, and a chemoattractant gradient, respectively. Here, we review sperm behavioral in these mechanisms and indicate commonalities and differences between them.
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