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Updated: Apr 12, 2026

A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
New directions for the treatment of adrenal insufficiency
Gerard Ruiz-Babot1, Irene Hadjidemetriou1, Peter James King1
1Centre for Endocrinology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London , London , UK.
Abstract:
Adrenal disease, whether primary, caused by defects in the hypothalamic-pituitary-adrenal (HPA) axis, or secondary, caused by defects outside the HPA axis, usually results in adrenal insufficiency, which requires lifelong daily replacement of corticosteroids. However, this kind of therapy is far from ideal as physiological demand for steroids varies considerably throughout the day and increases during periods of stress. The development of alternative curative strategies is therefore needed. In this review, we describe the latest technologies aimed at either isolating or generating de novo cells that could be used for novel, regenerative medicine application in the adrenocortical field.
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