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Updated: Apr 12, 2026

Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes
Published on: March 3, 2023
The complex epidemiology of extended-spectrum β-lactamase-producing Enterobacteriaceae
Ruthy Tal Jasper1, Joseph R Coyle, David E Katz2
11Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Abstract:
Antimicrobial resistance is a growing worldwide iatrogenic complication of modern medical care. Extended-spectrum β-lactamases have emerged as one of the most successful resistance mechanisms, limiting our therapeutic options to treat various human infections. The dissemination of these enzymes to the community probably signifies an irreversible step. This paper will review the evolution of human infections associated with extended-spectrum β-lactamase-producing organisms in the past 20 years, and will present and discuss the current challenges, controversies, debates and knowledge gaps in this research field.
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