Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pharmaceutical Poisoning: Potential Scenarios01:26

Pharmaceutical Poisoning: Potential Scenarios

97
Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...
97
Pharmacovigilance01:19

Pharmacovigilance

2.0K
Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
2.0K
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

360
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
360
Guidelines and Strategies for Safe Computer Charting01:18

Guidelines and Strategies for Safe Computer Charting

3.2K
The guidelines and strategies provided by the American Nurses Association (ANA) and the Canadian Nurses Association (CNA) offer essential principles for ensuring safe and secure computer charting systems in healthcare settings. Let's break down each recommendation:
Maintain Confidentiality and Security:
3.2K
Drug Toxicity: Risk factors01:24

Drug Toxicity: Risk factors

209
Adverse Drug Reactions (ADRs) are potential complications that arise during pharmacotherapy, influenced by multiple risk factors. Age plays a significant role; both neonates and the elderly are at heightened risk due to their respective immature and diminished metabolic and elimination processes. Gender also impacts ADRs, with females experiencing a 1.5 to 1.7-fold greater risk than males, which may be linked to pharmacokinetic, pharmacodynamic, and hormonal differences. Notably, neonates, the...
209
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

606
Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
606

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Developing a values-based interorganisational Care at the End-of-Life Collaborative framework for the Australian context: A mixed-methods, practice-based research protocol.

Palliative care and social practice·2025
Same author

Patient-centered Pharmacist Care in the Hemodialysis Unit: a quasi-experimental interrupted time series study.

BMC nephrology·2019
Same author

Evaluation of PHI Hunter in Natural Language Processing Research.

Perspectives in health information management·2016
Same author

The vulnerabilities of computerized physician order entry systems: a qualitative study.

Journal of the American Medical Informatics Association : JAMIA·2015
Same author

Design of a cluster-randomized trial of electronic health record-based tools to address overweight and obesity in primary care.

Clinical trials (London, England)·2015
Same author

An anesthesia medication cost scorecard--concepts for individualized feedback.

Journal of medical systems·2015
Same journal

Impact of Nursing Leadership for Surgical Excellence Program on Perioperative Care and Patient Safety in Low-Income Countries: A Mixed-Methods Study.

Journal of patient safety·2026
Same journal

Strengthening Telemetry Safety Through Standardized Physiological Parameter Monitor Technician Education: A Practice-Based Framework.

Journal of patient safety·2026
Same journal

Implementing Shortened Fasting Protocols Before Cardiac Catheterization: A Quality Improvement Initiative.

Journal of patient safety·2026
Same journal

A Qualitative Study Exploring the Views and Experiences of UK Maternity Healthcare Professionals Towards Adverse Event Disclosure.

Journal of patient safety·2026
Same journal

Clinical and Safety Outcomes of Patients Admitted to Different Specialty Wards: The Prospective, Multi-center, Controlled SISIFO Study.

Journal of patient safety·2026
Same journal

Responsive Learning and Proactive Harm Prevention: Development of a Tiered Event Review Continuum.

Journal of patient safety·2026
See all related articles

Related Experiment Video

Updated: Apr 12, 2026

E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy
06:28

E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy

Published on: August 1, 2019

9.4K

Ambulatory Computerized Prescribing and Preventable Adverse Drug Events.

Joseph Marcus Overhage1, Tejal K Gandhi, Carol Hope

  • 1From the *Siemens Health Services, Malvern, PA;, †Division of General Internal Medicine and Primary Care, Brigham and Women's Hospital; ‡Harvard Medical School, Boston, MA; §National Library of Medicine VA Medical Informatics Fellow, Salt Lake City, UT; ∥Purdue University College of Pharmacy, Indianapolis, IN; ¶Regenstrief Institute, Indianapolis, IN; and **Harvard School of Public Health, Boston, MA.

Journal of Patient Safety
|May 24, 2015
PubMed
Summary
This summary is machine-generated.

Computerized prescribing did not reduce preventable adverse drug events (ADEs) in ambulatory care. While potential ADEs decreased in Indianapolis, they increased in Boston, highlighting varied outcomes despite electronic health record implementation.

More Related Videos

Computerized Dynamic Posturography for Postural Control Assessment in Patients with Intermittent Claudication
14:52

Computerized Dynamic Posturography for Postural Control Assessment in Patients with Intermittent Claudication

Published on: December 11, 2013

12.3K
Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
07:13

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

Published on: April 12, 2021

5.4K

Related Experiment Videos

Last Updated: Apr 12, 2026

E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy
06:28

E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy

Published on: August 1, 2019

9.4K
Computerized Dynamic Posturography for Postural Control Assessment in Patients with Intermittent Claudication
14:52

Computerized Dynamic Posturography for Postural Control Assessment in Patients with Intermittent Claudication

Published on: December 11, 2013

12.3K
Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
07:13

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

Published on: April 12, 2021

5.4K

Area of Science:

  • Health Informatics
  • Patient Safety
  • Clinical Pharmacology

Background:

  • Adverse drug events (ADEs) are a significant cause of harm in ambulatory care.
  • Computerized physician order entry (CPOE) reduces medication errors in hospitals, but its impact on ambulatory ADEs is less studied.

Purpose of the Study:

  • To evaluate the effect of computerized prescribing with clinical decision support on preventable ADE rates in ambulatory settings.

Main Methods:

  • A before-and-after study design was employed.
  • Data were collected from adult patients in primary care practices at academic medical centers in Boston and Indianapolis.
  • Preventable ADEs were identified using structured results or symptoms from provider notes.

Main Results:

  • Computerized prescribing did not significantly alter preventable ADE rates at either site.
  • Potential ADE rates decreased in Indianapolis but increased in Boston.
  • Reasons for post-implementation ADEs included patient education, ignored clinical decision support system (CDSS) feedback, and incomplete knowledge bases.

Conclusions:

  • Computerized prescribing in ambulatory care did not reduce preventable ADEs.
  • The system showed mixed results for potential ADEs, decreasing them in Indianapolis while increasing them in Boston.
  • Absolute ADE rates remained lower in Boston compared to Indianapolis.