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Updated: Apr 12, 2026
Graphene Coatings for Biomedical Implants
Published on: March 1, 2013
Black hemostatic sponge based on facile prepared cross-linked graphene
Kecheng Quan1, Guofeng Li1, Di Luan1
1The State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, PR China.
A novel cross-linked graphene sponge (CGS) shows excellent hemostatic properties, rapidly absorbing plasma to promote blood clotting. This biocompatible material offers significant potential for effective trauma treatment.
Area of Science:
- Biomaterials Science
- Materials Chemistry
- Biomedical Engineering
Background:
- Hemostatic agents are critical for controlling bleeding in trauma.
- Graphene-based materials are being explored for biomedical applications due to their unique properties.
Purpose of the Study:
- To evaluate the hemostatic performance of a novel cross-linked graphene sponge (CGS).
- To investigate the mechanism behind the CGS's ability to accelerate blood coagulation.
Main Methods:
- Fabrication of a cross-linked graphene sponge (CGS).
- In vitro assessment of plasma absorption and blood clotting times.
- Analysis of blood cell-hemomaterial interactions at the interface.
Main Results:
- The CGS demonstrated rapid plasma absorption (<40 ms).
- The material effectively promoted blood coagulation by enriching hemocytes and platelets.
- In vitro dynamic whole-blood clotting tests confirmed the CGS's efficacy.
Conclusions:
- The cross-linked graphene sponge (CGS) is a highly effective hemostat.
- Its facile preparation, low cost, and biocompatibility make it promising for trauma management.
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