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Updated: Apr 12, 2026

Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis
Published on: September 26, 2018
[Diabetes, prediabetes and cardiovascular risk]
1Herz- und Diabeteszentrum NRW, Ruhr-Universität Bochum, Georgstr. 11, 32545, Bad Oeynhausen, Deutschland.
Insights
Diabetes mellitus significantly increases the risk of cardiovascular diseases, including coronary artery disease and heart failure. Managing glucose levels is crucial for mitigating vascular event risks in patients with diabetes.
Area of Science:
- Cardiology
- Endocrinology
- Public Health
Context:
- Cardiovascular diseases (CVDs) are a leading cause of death globally.
- Diabetes mellitus is a significant and growing risk factor for various CVDs.
- Many patients with CVDs also have metabolic issues like hypertension and dyslipoproteinaemia.
Purpose:
- To highlight the strong association between diabetes mellitus and cardiovascular diseases.
- To emphasize the increased risk of coronary artery disease, heart failure, and vascular events in diabetic patients.
- To underscore the impact of impaired glucose metabolism on cardiovascular health.
Summary:
- Diabetes mellitus is a major risk factor for cardiovascular diseases, including coronary artery disease and heart failure.
- Patients with diabetes often present with co-existing conditions like hypertension and dyslipoproteinaemia, further increasing cardiovascular risk.
- Impaired glucose metabolism is prevalent in patients with coronary artery disease, and diabetes significantly worsens outcomes for vascular events, atrial fibrillation, and heart failure, especially in women.
Impact:
- Highlights the critical need for integrated management of diabetes and cardiovascular risk factors.
- Emphasizes the importance of screening for glucose metabolism abnormalities in cardiovascular patients.
- Informs public health strategies aimed at reducing cardiovascular morbidity and mortality associated with diabetes.
Abstract:
Cardiovascular diseases continue to be the mainstay in morbidity and mortality in modern society with diabetes mellitus being a known risk factor for coronary artery disease, heart failure and vascular events. Most patients present with a combination of hypertension, dyslipoproteinaemia and (pre)diabetic metabolism potentiating the risk. From the perspective of organ damage two of three patients with coronary artery disease present with impaired glucose metabolism. In case of myocardial infarction 25-28% of patients do not present with impaired glucose metabolism. Women are more often affected than men and exhibit a more severe outcome, if diagnoses of vascular events and diabetes occur in parallel. Atrial fibrillation and heart failure are significantly associated with diabetes and significantly confer to the overall prognosis. Epidemiologically, the risk for vascular events is closely associated with the glucose burden of the affected patient.
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