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The effect of race on long term mortality in mechanically ventilated patients
Hatice Kaya1, Katherine E B Rider2, Richard L Amdur3
1Pulmonary, Critical Care and Sleep Medicine Division, The George Washington University MFA, USA; Gülhane Military Medical Faculty, Ankara, Turkey; TUBITAK Research Scholar, Ankara, Turkey.
Objective:
Determine the impact of race on one-year mortality following mechanical ventilation.
Background:
There is a lack of prospective studies on the effect of race on survival following mechanical ventilation.
Methods:
Observational study of adult patients on ventilatory support for <24 h prior to enrollment. Socioeconomic factors, laboratory and clinical data were recorded. Primary outcome was one-year mortality.
Results:
We enrolled 178 patients; 100 African American (AA), 78 other races (OTH). One-year mortality for AA was 49% and 33% for OTH (p = 0.035). After correcting for covariates, race was not significantly associated with mortality (p = 0.42). AA patients had higher mean arterial blood pressure, serum creatinine, heart rate, and peak (p < 0.01) and mean (p = 0.05) airway pressures.
Conclusions:
AA patients who underwent mechanical ventilation had greater one-year mortality, although race per se was not a significant factor. It remains to be determined if strict blood pressure control and lower airway pressures may improve survival in this racial group.
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