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Bacterial Endocarditis Manifesting as Outflow Tract Obstruction in Two Patients Implanted With Percutaneous
Nadia Chaudhry-Waterman1, Lisa Bergersen1, Jonathan Buber1
1Department of Cardiology, Boston Children's Hospital, Boston, Massachusetts, USA.
Abstract:
Recent reports on bacterial infections occurring in patients with transcatheter-implanted pulmonary valves have raised concerns about higher than previously perceived occurrences of these events. We report on 2 patients who presented with right ventricular outflow tract obstruction secondary to prosthetic pulmonary valve endocarditis involving the valve's periphery, a rarely described and uncommon manifestation. One patient had an acute and rapidly deteriorating disease course, whereas the other had a more chronic and indolent course. Both patients were treated in the catheterization laboratory to relieve the obstructions, treatments which resulted in satisfactory acute results.
Insights
Bacterial endocarditis can affect the periphery of transcatheter pulmonary valves, causing obstruction. This study presents two cases with differing disease courses, both successfully treated with catheterization procedures.
Area of Science:
- Cardiology
- Infectious Diseases
- Medical Devices
Background:
- Transcatheter pulmonary valves are increasingly used, but bacterial infection is a concern.
- Prosthetic valve endocarditis (PVE) is a serious complication.
- Peripheral endocarditis is a rare presentation of PVE.
Observation:
- Two patients with transcatheter pulmonary valves developed right ventricular outflow tract obstruction.
- The obstruction was due to prosthetic pulmonary valve endocarditis involving the valve periphery.
- One patient experienced acute, rapidly worsening symptoms, while the other had a chronic, slow-progressing condition.
Findings:
- Peripheral endocarditis of transcatheter pulmonary valves is an uncommon but significant cause of obstruction.
- The clinical presentation can vary from acute to chronic.
- Catheterization procedures can effectively relieve the obstruction in the acute setting.
Implications:
- Increased vigilance for peripheral endocarditis in patients with transcatheter pulmonary valves is warranted.
- Early diagnosis and intervention are crucial for managing this complication.
- Catheter-based interventions offer a viable treatment option for relieving obstruction.
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