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Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
Published on: January 9, 2015
Contemporary models of pediatric obsessive-compulsive disorder: An evaluation with a large clinical sample
Alessandro De Nadai1, Prianka S Nagpal2, John Piacentini3
1Department of Psychology, University of South Florida, 4202 East Fowler Ave, PCD 4118G Tampa, FL 33620, United States; Departments of Pediatrics and Psychiatry, Rothman Center for Neuropsychiatry, University of South Florida College of Medicine, 880 6th Street South, Suite 460, Saint Petersburg, FL 33701, United States.
Abstract:
We evaluated the construct validity of the Child Yale-Brofwn Obsessive-Compulsive Scale (CYBOCS) in a large clinical sample (N=730) using confirmatory factor analysis. Results found inadequate fit for a priori models, though a model accounting for overlapping item content displayed good fit. Parallel obsessions/compulsions items may provide largely redundant information on the CYBOCS. Findings suggest modifying the CYBOCS to reduce burden on researchers, patients, and clinicians, and to more accurately measure pediatric obsessive-compulsive disorder (OCD).
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