Primary and secondary prevention of ischemic heart disease in women

Priya Kohli1

  • 1Division of Cardiovascular Medicine, West Roxbury Veterans' Administration Hospital, 1400 VFW Parkway, West Roxbury, MA, 02132, USA, priya-kohli@fsm.northwestern.edu.

Insights

Cardiovascular disease mortality in women has decreased, yet remains higher than in men, especially in younger women. This review examines primary and secondary prevention therapies for ischemic heart disease in women.

Area of Science:

  • Cardiology
  • Women's Health
  • Preventive Medicine

Background:

  • Cardiovascular disease (CVD) is the leading cause of death for women globally.
  • While awareness and trial inclusion for women have improved, leading to reduced CVD mortality, women still experience higher mortality rates than men.
  • There is a concerning rise in CVD among younger women, highlighting an unmet need for effective prevention strategies.

Purpose of the Study:

  • To review current data on primary and secondary prevention therapies for ischemic heart disease (IHD) specifically in women.
  • To identify gaps and opportunities in the prevention of IHD in the female population.
  • To inform clinical practice and future research directions for women's cardiovascular health.

Main Methods:

  • Comprehensive literature search of clinical trials and observational studies.
  • Analysis of data focusing on the efficacy and safety of preventive therapies in women.
  • Synthesis of evidence regarding primary and secondary prevention strategies for ischemic heart disease.

Main Results:

  • Data indicates a decline in cardiovascular disease mortality among women due to increased awareness and trial participation.
  • Despite progress, women continue to have higher mortality rates from cardiovascular disease compared to men.
  • An increasing incidence of cardiovascular disease is observed in younger women, underscoring the need for targeted preventive measures.

Conclusions:

  • Preventive therapies are crucial for addressing the persistent gap in cardiovascular disease outcomes between men and women.
  • Continued research and guideline development focusing on women are essential for reducing the burden of ischemic heart disease.
  • Implementing evidence-based preventive strategies is key to improving cardiovascular health and reducing mortality in women across all age groups.

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