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Discovery of MK-1421, a Potent, Selective sstr3 Antagonist, as a Development Candidate for Type 2 Diabetes

Shrenik K Shah1, Shuwen He1, Liangqin Guo1

  • 1Departments of Medicinal Chemistry, Chemistry Modeling and Infomatics, Drug Metabolism and Pharmacokinetics, and Diabetes Research, Merck Research Laboratories , 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.

ACS Medicinal Chemistry Letters
|May 26, 2015
PubMed

Keywords:
antagonistsstr3tetrahydro-β-carbolinetype 2 diabetes

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