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In vitro acid decalcification of human surface enamel pretreated with toothpaste slurries
E Tadmor1, P Poitou, I Gedalia
1Dental Research Unit, Faculty of Dentistry, Hebrew University, Hadassah Medical School, Jerusalem, Israel.
Journal of Oral Rehabilitation
|November 1, 1989
Summary
Organic fluoride toothpastes enhance tooth enamel resistance to demineralization. This study investigated inorganic fluoride (NaF) and organic fluoride toothpaste effects on enamel, finding organic fluoride superior in preventing cavities.
Area of Science:
- Biomaterials Science
- Dental Research
- Fluoride Chemistry
Background:
- Dental caries is a prevalent oral disease caused by demineralization of tooth enamel.
- Fluoride is a key agent in preventing dental caries through remineralization and inhibiting demineralization.
- Different forms of fluoride, including inorganic and organic, are used in oral hygiene products.
Purpose of the Study:
- To evaluate the efficacy of organic fluoride compounds in comparison to inorganic fluoride (sodium fluoride) in preventing enamel demineralization.
- To assess the impact of amine fluoride and sodium fluoride toothpaste slurries on tooth enamel's resistance to a caries-like challenge.
- To determine the protective effects of different fluoride formulations on human tooth enamel in an in vitro setting.
Main Methods:
- An in vitro model simulating a caries-like challenge was employed.
- Human tooth enamel samples were treated with slurries of toothpastes containing either inorganic fluoride (sodium fluoride) or organic fluorides (aliphatic and aromatic amine fluorides).
- The resistance of the treated enamel to demineralization was subsequently measured.
Main Results:
- Tooth enamel treated with organic fluoride-containing toothpaste slurries demonstrated enhanced resistance to demineralization.
- The positive effect on enamel resistance was observed when using aliphatic and aromatic amine fluorides.
- Inorganic fluoride (sodium fluoride) also provided protection, but organic fluoride formulations showed a notable positive impact.
Conclusions:
- Organic fluoride compounds, specifically aliphatic and aromatic amine fluorides, significantly improve the resistance of human tooth enamel to demineralization.
- These findings suggest that organic fluoride toothpastes may offer superior protection against dental caries compared to traditional inorganic fluoride formulations.
- Further clinical studies are warranted to confirm the in vitro findings regarding the anticariogenic potential of organic fluoride toothpastes.