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Multiple sclerosis in India: An institutional study.

Ankit Singhal1, Rohit Bhatia1, M V Padma Srivastava1

  • 1Department of Neurology, All India Institute of Medical Sciences, New Delhi, India.

Multiple Sclerosis and Related Disorders
|May 27, 2015
PubMed
Summary
This summary is machine-generated.

This study establishes a multiple sclerosis (MS) patient registry in India, finding demographic data comparable to Western populations. A nationwide registry is crucial for understanding MS incidence and prevalence in India.

Keywords:
DemyelinationDisease modifying therapyMultiple sclerosisMyelitisOptic neuritis

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Area of Science:

  • Neurology
  • Epidemiology
  • Clinical Research

Background:

  • Limited population-based studies on multiple sclerosis (MS) exist in India.
  • Growing demand for a national MS registry due to perceived increases in incidence and prevalence.
  • Understanding MS disease characteristics in the Indian population is essential.

Purpose of the Study:

  • To establish a registry database for MS patients at the institute.
  • To analyze the characteristics of MS in the Indian population.
  • To compare Indian MS patient data with international reports.

Main Methods:

  • Diagnosis of MS based on Revised McDonald criteria (2010).
  • Collection of demographic, clinical, treatment, and disease behavior data.
  • Descriptive analysis of data over a one-year follow-up.

Main Results:

  • 101 MS patients (61 female) recruited; mean age 33.3 years.
  • Relapsing-remitting MS (RRMS) was most common (68.4%).
  • Spinal cord involvement in the first relapse (43.7%) and comparable characteristics to Western populations.

Conclusions:

  • Demographic data of Indian MS patients align with Western epidemiological studies.
  • A nationwide MS registry is vital for robust data on incidence, prevalence, and disease profiles in India.
  • Further research and registry establishment are recommended for comprehensive MS understanding in India.