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Sclerotiorin is non-mutagenic and inhibits human PMNL 5-lipoxygenase and platelet aggregation
Indian Journal of Experimental Biology
|May 28, 2015
Abstract:
Sclerotiorin, isolated from the fermented broth of Penicillium frequentans, exhibited potent inhibition against human polymorphonuclear leukocytes 5-lipoxygenase and human platelet aggregation with a half maximal value 36 μM and 250 μM, respectively. Further, the Ames test has demonstrated the sclerotiorin to be non-mutagenic.

