[Familial hypercholesterolemia: why screening, counselling and treatment should be integrated]

Area of Science:

• Genetics
• Cardiology
• Public Health

Background:

• Familial hypercholesterolemia (FH) is a common, inherited disorder causing high cholesterol and premature cardiovascular disease (CVD).
• Effective drug therapies are available for FH patients.
• The Netherlands previously pioneered a national FH screening program.

Purpose of the Study:

• To propose an integrated and cost-effective approach for Familial hypercholesterolemia (FH) detection, counseling, and treatment.
• To ensure continued efficient FH care following the discontinuation of the national screening program.

Main Methods:

• The study proposes integrating FH screening, counseling, and treatment coordination.
• This integration is suggested to be managed by healthcare providers currently treating FH patients.

Main Results:

• The discontinuation of the national screening program necessitates a new model for FH care.
• Integrating FH detection within existing healthcare structures is essential for efficiency.

Conclusions:

• Coordinated care by treating physicians can ensure efficient and cost-effective detection, counseling, and treatment of FH.
• This integrated approach aims to maintain the Netherlands' role in pioneering FH management.