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The hepatoprotective principle of Hypoestes triflora leaves
L Van Puyvelde1, A Kayonga, P Brioen
1Centre Universitaire de Recherche sur la Pharmacopée et la Médecine Traditionnelle, Faculté des Sciences, Université Nationale du Rwanda, France.
Journal of Ethnopharmacology
|September 1, 1989
Abstract:
Hypoestes triflora is frequently used in Rwandese native medicine to treat hepatic diseases. Premedication with a water extract of the leaves prevented the prolongation of the barbiturate sleeping time associated with carbon tetrachloride-induced liver damage in mice. The compound responsible for this protective activity was benzoic acid. Mice previously treated with benzoic acid also showed a significant diminution of the increased GOT and GPT levels seen after carbon tetrachloride administration.