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Management of consecutive development of ruptured intracranial mycotic aneurysms: case report
Ke Wang1, Jiping Sun, Xiang Zhang
1Tongji University, Shanghai Tenth People's Hospital, Neurosurgical Department, Shanghai, China.
Abstract:
Intracranial mycotic aneurysm (MA), also known as intracranial infectious aneurysm, is a rare type of intracranial aneurysm. However, it carries a high mortality rate of 80% when ruptured and 30% even when unruptured. Here we report a 22-year-old male patient who consecutively developed two ruptured intracranial MAs related to infective endocarditis. The time interval between the two attacks was approximately seven months. The second aneurysm formed and ruptured regardless of long-term antibiotic therapy and cardiac surgery to replace the dysfunctional aortic valve. This case indicates that intracranial MAs may develop even after successful treatment of the underlying cardiac disorders, and hence close angiographic follow-ups may be warranted following the cardiac surgery.
Insights
Intracranial mycotic aneurysms (MAs) are rare but dangerous. This case shows MAs can recur even after treating infective endocarditis and cardiac surgery, necessitating ongoing monitoring.
Area of Science:
- Neurology
- Cardiology
- Infectious Diseases
Background:
- Intracranial mycotic aneurysms (MAs), or infectious aneurysms, are rare vascular lesions with high morbidity and mortality.
- Ruptured MAs carry an 80% mortality rate, while unruptured MAs have a 30% mortality rate.
Observation:
- A 22-year-old male presented with two consecutive ruptured intracranial MAs.
- The MAs were linked to infective endocarditis, occurring seven months apart.
- The second MA developed and ruptured despite prolonged antibiotic treatment and aortic valve replacement surgery.
Findings:
- Intracranial mycotic aneurysms can recur even after successful management of the underlying infective endocarditis and cardiac repair.
- The formation and rupture of a second MA highlight the persistent risk associated with this condition.
Implications:
- Patients with a history of intracranial MAs require vigilant, long-term angiographic surveillance, even after seemingly curative interventions.
- This case underscores the complex management of MAs and suggests current treatment paradigms may need re-evaluation for persistent risks.
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