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Published on: December 12, 2025
Distribution of Epididymal Involvement in Mumps Epididymo-orchitis
Seong Jin Park1, Hyun Cheol Kim2, Joo Won Lim2
1Department of Diagnostic Radiology, Kyung Hee University Hospital, College of Medicine, Kyung Hee University, Seoul, Korea. indawn@hanafos.com.
Objectives:
To evaluate characteristic sonographic findings for mumps orchitis with epididymal involvement.
Methods:
This study included 18 patients (aged 12-18 years) with mumps orchitis. We assessed the volume, echogenicity, and vascularity of the testes and the transverse diameter, echogenicity, and vascularity of the epididymal head, body, and tail. We classified 4 types of epididymal involvement: 1A, focal swelling of the epididymal head with hypervascularity only on the swollen head; 1B, focal swelling of the epididymal head with hypervascularity on the entire epididymis; 1C, diffuse swelling of the entire epididymis with hypervascularity; and 2, no epididymal involvement. The Student t test was used to evaluate the significance of the size of each part of the epididymis and the epididymal head-to-tail diameter ratio.
Results:
Orchitis was unilateral in 13 patients and bilateral in 5. Of 23 affected hemiscrotums, 7 (30.4%) were type 1A, 4 (17.4%) type 1B, 2 (8.7%) type 1C, and 10 (43.5%) type 2. In 11 patients with unilateral epididymal involvement, the mean diameters ± SDs of the epididymal heads on the affected and contralateral sides were 1.11 ± 0.19 (range, 0.7-1.7) and 0.65 ± 0.14 (0.3-0.9) cm (significantly different, P <.001). The diameters of the epididymal tails on the affected and contralateral sides were 0.51 ± 0.41 (0.2-0.8) and 0.46 ± 0.21 (0.3-0.6) cm (not statistically different, P = .106). The mean head-to-tail ratios on the affected and contralateral sides were 2.28 ± 0.49 (1.29-3.00) and 1.41 ± 0.22 (1.00-1.75; significantly different, P < .001). In all types 1A and 1B, the ratio was higher than 2.00; in 22 of 23 unaffected epididymides, the ratio was lower than 2.00.
Conclusions:
Focal swelling of epididymal heads was a characteristic sonographic finding of mumps epididymo-orchitis, and a head-to-tail ratio higher than 2.00 can be a useful diagnostic finding.
Insights
Sonography reveals focal swelling of the epididymal head in mumps epididymo-orchitis. An epididymal head-to-tail diameter ratio greater than 2.00 is a key diagnostic indicator.
Area of Science:
- Pediatric Radiology
- Ultrasound Imaging
- Infectious Diseases
Background:
- Mumps orchitis is a common complication of mumps in postpubertal males.
- Epididymal involvement frequently accompanies mumps orchitis, necessitating accurate diagnostic methods.
- Sonography plays a crucial role in evaluating scrotal pathology, including epididymo-orchitis.
Purpose of the Study:
- To identify characteristic sonographic findings associated with mumps orchitis.
- To specifically evaluate sonographic features of epididymal involvement in mumps epididymo-orchitis.
- To determine the diagnostic utility of specific sonographic measurements, such as the epididymal head-to-tail ratio.
Main Methods:
- Retrospective analysis of 18 male patients (aged 12-18 years) diagnosed with mumps orchitis.
- Sonographic assessment of testicular and epididymal parameters: volume, echogenicity, vascularity, and diameters.
- Classification of epididymal involvement into four types (1A, 1B, 1C, and 2) based on swelling and vascularity.
- Statistical analysis using the Student t test to compare affected and contralateral sides and evaluate the head-to-tail ratio.
Main Results:
- Orchitis was unilateral in 13 patients and bilateral in 5.
- Epididymal involvement was observed in 13 out of 23 affected hemiscrotums (types 1A, 1B, 1C).
- Significantly increased epididymal head diameters (P < .001) and head-to-tail ratios (P < .001) were noted on the affected side.
- A head-to-tail ratio > 2.00 was consistently found in mumps epididymitis (types 1A and 1B) but not in unaffected epididymides.
Conclusions:
- Focal swelling of the epididymal head is a characteristic sonographic finding in mumps epididymo-orchitis.
- An epididymal head-to-tail diameter ratio exceeding 2.00 is a valuable sonographic marker for diagnosing mumps epididymitis.
- Sonographic evaluation of epididymal morphology, particularly the head-to-tail ratio, aids in differentiating mumps-related scrotal inflammation.
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