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Related Experiment Video

Updated: Apr 11, 2026

Isolation, Processing and Analysis of Murine Gingival Cells
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Plasma cell gingivitis.

Chandershekhar Joshi1, Pradeep Shukla1

  • 1Department of Periodontics and Implantology, DJ College of Dental Sciences and Research, Modinagar, Uttar Pradesh, India.

Journal of Indian Society of Periodontology
|May 28, 2015
PubMed
Summary

Plasma cell gingivitis (PCG) is a rare gum condition linked to herbal toothpowder hypersensitivity. Discontinuing the product led to symptom resolution, highlighting the need for awareness of herbal product effects.

Area of Science:

  • Oral Medicine
  • Dermatology
  • Immunology

Background:

  • Plasma cell gingivitis (PCG) is a rare, benign gingival condition.
  • Characterized by significant plasma cell infiltration into sub-epithelial gingival tissue.
  • Often a hypersensitivity reaction to antigens like flavoring agents in oral products.

Observation:

  • A case report details a 27-year-old male with painful, bleeding, swollen gums.
  • Symptoms were associated with prolonged use of herbal toothpowder.
  • Clinical presentation included erythematous, edematous gingivitis and bleeding on probing.

Findings:

  • Discontinuation of the herbal toothpowder, combined with periodontal treatment, resolved the condition.
  • No recurrence was observed after removing the suspected antigen.
Keywords:
Biopsyherbal toothpowderplasma cell gingivitis

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  • This case underscores the potential for PCG to develop from herbal oral care products.

    • Implications:

    • Clinicians must be aware of PCG's potential link to popular herbal products.
    • Early diagnosis is crucial, as PCG mimics serious conditions like leukemia and autoimmune diseases.
    • Distinguishing PCG requires hematologic and serologic testing to rule out other pathologies.