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Bilateral angle closure glaucoma following general anaesthesia.

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An Alkali-burn Injury Model of Corneal Neovascularization in the Mouse
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Significance of corneal arcus.

K Mohan Raj1, P Arun Subhash Reddy1, Vikram Chella Kumar1

  • 1Department of Ophthalmolgy, Sree Balaji Medical College, Chromepet, Chennai, Tamil Nadu, India.

Journal of Pharmacy & Bioallied Sciences
|May 28, 2015
PubMed
Summary

Corneal arcus, a lipid deposit in the eye, is strongly linked to elevated serum triglycerides. This finding highlights the importance of monitoring lipid metabolism for eye health, especially with increasing age.

Keywords:
Arcus seniliscataractlow density lipo proteinsserum cholesteroltriglycerides

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Area of Science:

  • Ophthalmology
  • Lipid Metabolism
  • Biochemistry

Background:

  • Corneal arcus is an eye condition characterized by lipid deposits.
  • Serum triglyceride levels are key indicators of lipid metabolic health.

Purpose of the Study:

  • To investigate the correlation between corneal arcus and serum triglyceride levels.
  • To assess the role of lipid metabolism impairment in corneal arcus incidence.

Main Methods:

  • Analysis of corneal arcus composition.
  • Measurement of serum triglyceride levels in patients.
  • Statistical correlation analysis with age.

Main Results:

  • Corneal arcus is composed of cholesterol, phospholipids, and triglycerides.
  • Serum triglyceride levels were elevated in 72% of patients with corneal arcus.
  • A positive correlation was observed between elevated triglycerides, corneal arcus, and increasing age.

Conclusions:

  • Impaired lipid metabolism is strongly associated with the development of corneal arcus.
  • Serum triglyceride levels serve as a significant biomarker for corneal arcus risk.
  • Age is a contributing factor in the relationship between lipid metabolism and corneal arcus.