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Oral lichen planus: An overview.

R Jayasri Krupaa1, S Leena Sankari1, K M K Masthan1

  • 1Department of Oral Pathology and Microbiology, Sree Balaji Dental College and Hospital, Bharath University, Chennai, Tamil Nadu, India.

Journal of Pharmacy & Bioallied Sciences
|May 28, 2015
PubMed
Summary
This summary is machine-generated.

Oral lichen planus (OLP) and oral lichenoid reactions (OLR) are distinct conditions requiring accurate diagnosis. Differentiating OLP from OLR is crucial for effective treatment and prognosis.

Keywords:
Betel quid lichenoid lesionGrinspan syndromecorticosteroidsmalignant transformationoral lichen planusoral lichenoid reactionphotochemotherapyretinoidsvulvovaginal-gingival syndrome

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Area of Science:

  • Immunology
  • Dermatology
  • Oral Medicine

Background:

  • Lichen planus is an immunologically mediated mucocutaneous disease with diverse triggers.
  • Oral lichenoid reactions are often considered a variant but require separate diagnosis from oral lichen planus.
  • The condition can manifest in various clinical forms and affect multiple body sites, including oral mucosa, skin, and internal organs.

Purpose of the Study:

  • To elucidate the key differences between oral lichen planus and oral lichenoid reactions.
  • To emphasize the importance of accurate diagnosis for appropriate treatment strategies.
  • To highlight the varied clinical presentations and potential systemic associations of lichen planus.

Main Methods:

  • Review of existing literature on oral lichen planus and oral lichenoid reactions.
  • Analysis of etiological factors and cause-effector relationships.
  • Comparison of clinical manifestations, prognosis, and treatment protocols.

Main Results:

  • Oral lichenoid reactions exhibit a strict cause-effector relationship, differentiating them from oral lichen planus.
  • Lichen planus presents with varied clinical forms and prognoses, and can be associated with systemic conditions like hypertension and diabetes mellitus.
  • Malignant transformation has been reported, underscoring the need for careful examination and follow-up.

Conclusions:

  • Distinguishing oral lichen planus from oral lichenoid reactions is essential for effective management.
  • Understanding the varied clinical presentations and potential systemic links is vital for comprehensive patient care.
  • Regular follow-up and meticulous examination are necessary due to the risk of malignant transformation.