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Frataxin Accelerates [2Fe-2S] Cluster Formation on the Human Fe-S Assembly Complex

Nicholas G Fox, Deepika Das, Mrinmoy Chakrabarti

    Biochemistry
    |May 29, 2015
    PubMed
    Summary

    Frataxin (FXN) accelerates the synthesis of [2Fe-2S] clusters, not [4Fe-4S] clusters, in human mitochondria. This corrects previous findings and clarifies FXN's role in iron-sulfur cluster assembly.

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