Related Experiment Video
Updated: Apr 11, 2026
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Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model
Published on: August 17, 2022
3.3K
[Living liver donor: indications and technical aspects]
S Nadalin1, I Capobianco, I Königsrainer
1Klinik für Allgemeine, Viszeral- und Transplantationschirurgie, Universitätsklinikum Tübingen, Hoppe-Seyler-Str. 3, 72076, Tübingen, Deutschland.
Summary
Living donor liver transplantation (LDLT) is a safe alternative to deceased donor liver transplantation (DDLT). Donor safety is paramount, with low mortality rates (0.1-0.5%) for hepatectomy procedures.
Area of Science:
- Hepatology
- Transplant Surgery
- Surgical Safety
Context:
- Living donor liver transplantation (LDLT) is increasingly utilized as a viable alternative to deceased donor liver transplantation (DDLT).
- Donor safety remains a critical consideration due to the inherent risks of major surgery on healthy individuals.
Purpose:
- To review the indications for LDLT.
- To detail the technical aspects of donor hepatectomy.
- To present donor selection criteria, evaluation methods, and associated morbidity and mortality outcomes.
Summary:
- Indications for LDLT largely mirror those for DDLT.
- Donor hepatectomy involves five key phases: right, left, or left lateral approaches.
- Reported morbidity ranges from 10% to 60%, influenced by center experience; postoperative mortality for left and right hepatectomy is low (0.1% and 0.5%, respectively).
Impact:
- LDLT offers comparable or superior outcomes to DDLT for specific patient indications.
- Highlights the importance of experienced transplant centers in minimizing donor complications.
- Provides essential data for refining donor safety protocols and patient selection in LDLT.
