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A case of perforating folliculitis in association with antisynthetase syndrome

K C Shaw1, J R Kaley2, M D Darling2

  • 1University of Maryland School of Medicine, Baltimore, MD USA.

Journal of Biological Regulators and Homeostatic Agents
|May 29, 2015
PubMed

Insights

Perforating folliculitis, a skin condition, can occur with autoimmune diseases. This case study details perforating folliculitis developing in a patient with antisynthetase syndrome.

Area of Science:

  • Dermatology
  • Rheumatology
  • Internal Medicine

Background:

  • Perforating folliculitis (PF) is characterized by follicular papules resulting from altered dermal material elimination through the epidermis.
  • PF is frequently associated with systemic conditions such as diabetes mellitus (DM) and chronic renal failure (CRF).
  • Acquired perforating dermatosis is a broader classification encompassing PF, Kyrle\'s disease, and perforating collagenosis.

Purpose of the Study:

  • To report a rare case of perforating folliculitis.
  • To describe the occurrence of PF in the context of antisynthetase syndrome.

Main Methods:

  • Case report detailing clinical presentation and patient history.
  • Review of existing literature on perforating folliculitis and antisynthetase syndrome.

Main Results:

  • The patient presented with clinical features consistent with perforating folliculitis.
  • The onset of PF was observed in a patient with a pre-existing diagnosis of antisynthetase syndrome.

Conclusions:

  • Perforating folliculitis can manifest in patients with autoimmune conditions like antisynthetase syndrome.
  • This association highlights the potential systemic links to acquired perforating dermatoses.

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